Serotonin regulates many physiological processes including sleep, appetite, and mood.
Thus, serotonergic system is an important target in the treatment of psychiatric disorders …

The 1, 8‐naphthyridine group of compounds have gained special attention of researchers
on account of their demonstrating a variety of interesting biological activities. A wide range of …

Abstract Serotonin (5‐hydroxytryptophan [5‐HT]) is a biologically active amine expressed in
platelets, in gastrointestinal (GI) cells and, to a lesser extent, in the central nervous system …

1, 8-Naphthyridine nucleus belongs to significant nitrogen-containing heterocyclic
compounds which has garnered the interest of researchers due to its versatile biological …

Background and Purpose It has recently been suggested that 5‐HT3 receptor blockade
enhances the efficacy of selective 5‐HT (serotonin) reuptake inhibitor (SSRI) …

Depression and anxiety are the most debilitating mood disorders with poor therapeutic
recovery rates. In the last decades, 5-HT 3 receptor antagonists have been identified as …

Within the wide range of nitrogen-containing heterocyclic compounds, the derivatives of 1, 8-
naphthyridine (NPTR) have gained a rising interest due to their reported versatile biological …

A series of spiro β‐Lactams (4 a–c, 7 a–c) and thiazolidinones (5 a–c, 8 a–c) possessing 1,
8‐naphthyridine moiety were synthesized in this study. The structure of the newly …

Previously, we have shown that anabolic androgenic steroid (AAS) exposure throughout
adolescence stimulates offensive aggression while also reducing anxious behaviors during …

This article presents a review of studies of new pharmacological substances in the aspect of
their anxiolytic activity. These substances are derivatives of various chemical classes. The …