Functional role and mechanisms of sialyllactose and other sialylated milk oligosaccharides

SJM ten Bruggencate, IMJ Bovee-Oudenhoven… - Nutrition …, 2014 - academic.oup.com
Human milk is a rich source of oligosaccharides. Acidic oligosaccharides, such as
sialyllactose (SL), contain sialic acid (SA) residues. In human milk, approximately 73% of SA …

Silkworm expression system as a platform technology in life science

T Kato, M Kajikawa, K Maenaka, EY Park - Applied microbiology and …, 2010 - Springer
Many recombinant proteins have been successfully produced in silkworm larvae or pupae
and used for academic and industrial purposes. Several recombinant proteins produced by …

Significant role of host sialylated glycans in the infection and spread of severe acute respiratory syndrome coronavirus 2

W Saso, M Yamasaki, S Nakakita, S Fukushi… - PLoS …, 2022 - journals.plos.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been transmitted
across all over the world, in contrast to the limited epidemic of genetically-and virologically …

Sialic acid-mimic peptides as hemagglutinin inhibitors for anti-influenza therapy

T Matsubara, A Onishi, T Saito, A Shimada… - Journal of medicinal …, 2010 - ACS Publications
Influenza is an infectious disease caused by the influenza virus, and each year many people
suffer from this disease. Hemagglutinin (HA) in the membrane of type A influenza viruses …

Protecting-group-free synthesis of glycopolymers bearing sialyloligosaccharide and their high binding with the influenza virus

T Tanaka, H Ishitani, Y Miura, K Oishi… - ACS Macro …, 2014 - ACS Publications
Glycopolymers having pendant triazole-linked sialyloligosaccharides were successfully
synthesized from free saccharides without any protection of the hydroxy and carboxy groups …

Role of the key mutation in the selective binding of avian and human influenza hemagglutinin to sialosides revealed by quantum-mechanical calculations

T Sawada, DG Fedorov, K Kitaura - Journal of the American …, 2010 - ACS Publications
The selective binding between avian and human influenza A viral hemagglutinins (HA)
subtype H3 and Neu5Acα2-3 and α2-6Gal (avian α2-3, human α2-6) is qualitatively …

Carbohydrate-functionalized chitosan fiber for influenza virus capture

X Li, P Wu, GF Gao, S Cheng - Biomacromolecules, 2011 - ACS Publications
The high transmissibility and genetic variability of the influenza virus have made the design
of effective approaches to control the infection particularly challenging. The virus surface …

Glucosyl hesperidin prevents influenza a virus replication in vitro by inhibition of viral sialidase

RK Saha, T Takahashi, T Suzuki - Biological and Pharmaceutical …, 2009 - jstage.jst.go.jp
MATERIALS AND METHODS Reagents Glucosyl hesperidin (GH) was a generous gift from
Hayashibara Biochemical Laboratories (Okayama, Japan). Minimum essential medium …

Synthesis of sialoclusters appended to calix [4] arene platforms via multiple azide-alkyne cycloaddition. New inhibitors of hemagglutination and cytopathic effect …

A Marra, L Moni, D Pazzi, A Corallini, D Bridi… - Organic & …, 2008 - pubs.rsc.org
Tetra-and octavalent sialoside clusters were prepared in good yields exploiting for the first
time the multiple copper-catalyzed cycloaddition of a propargyl thiosialoside with calix [4] …

PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acid

L Bondioli, L Costantino, A Ballestrazzi, D Lucchesi… - Biomaterials, 2010 - Elsevier
There is a broad interest in the development of nanoparticles (NPs) carrying on their surface
carbohydrates such as sialic acids. It is known that these carbohydrates influence the …