[HTML][HTML] Stem cell-based therapy for human diseases

DM Hoang, PT Pham, TQ Bach, ATL Ngo… - Signal transduction and …, 2022 - nature.com
Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies

HR Hofer, RS Tuan - Stem cell research & therapy, 2016 - Springer
Adult mesenchymal stem cells (MSCs) represent a subject of intense experimental and
biomedical interest. Recently, trophic activities of MSCs have become the topic of a number …

Conditioned media derived from mesenchymal stem cell cultures: The next generation for regenerative medicine

TNA Gunawardena, MT Rahman… - Journal of tissue …, 2019 - Wiley Online Library
Recent studies suggest that the main driving force behind the therapeutic activity observed
in mesenchymal stem cells (MSCs) are the paracrine factors secreted by these cells. These …

Translational considerations in injectable cell-based therapeutics for neurological applications: concepts, progress and challenges

MH Amer, FRAJ Rose, KM Shakesheff… - NPJ Regenerative …, 2017 - nature.com
Significant progress has been made during the past decade towards the clinical adoption of
cell-based therapeutics. However, existing cell-delivery approaches have shown limited …

[HTML][HTML] Human induced pluripotent stem cell–derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis

D Povero, EM Pinatel, A Leszczynska, NP Goyal… - JCI insight, 2019 - ncbi.nlm.nih.gov
Progression of fibrosis and the development of cirrhosis are responsible for the liver-related
morbidity and mortality associated with chronic liver diseases. There is currently a great …

Optimal H2O2 preconditioning to improve bone marrow mesenchymal stem cells' engraftment in wound healing

L Guo, J Du, D Yuan, Y Zhang, S Zhang… - Stem cell research & …, 2020 - Springer
Background The transplantation of bone marrow mesenchymal stem cells (BMSCs) is a
promising therapeutic strategy for wound healing. However, the poor migration capacity and …

Adipose stem cell translational applications: from bench-to-bedside

C Argentati, F Morena, M Bazzucchi… - International journal of …, 2018 - mdpi.com
During the last five years, there has been a significantly increasing interest in adult adipose
stem cells (ASCs) as a suitable tool for translational medicine applications. The abundant …

From bench to bedside: use of human adipose-derived stem cells

V Feisst, S Meidinger, MB Locke - Stem cells and cloning …, 2015 - Taylor & Francis
Since the discovery of adipose-derived stem cells (ASC) in human adipose tissue nearly 15
years ago, significant advances have been made in progressing this promising cell therapy …

Translational potential of mesenchymal stem cells in regenerative therapies for human diseases: challenges and opportunities

S Zhidu, T Ying, J Rui, Z Chao - Stem Cell Research & Therapy, 2024 - Springer
Advances in stem cell technology offer new possibilities for patients with untreated diseases
and disorders. Stem cell-based therapy, which includes multipotent mesenchymal stem cells …

All‐trans retinoic acid preconditioning enhances proliferation, angiogenesis and migration of mesenchymal stem cell in vitro and enhances wound repair in vivo

M Pourjafar, M Saidijam, K Mansouri… - Cell …, 2017 - Wiley Online Library
Objectives Stem cell therapy is considered to be a suitable alternative in treatment of a
number of diseases. However, there are challenges in their clinical application in cell …