[HTML][HTML] Hepatitis B virus PreS/S gene variants: pathobiology and clinical implications

T Pollicino, I Cacciola, F Saffioti, G Raimondo - Journal of hepatology, 2014 - Elsevier
The emergence and takeover of hepatitis B virus (HBV) variants carrying mutation (s) in the
preS/S genomic region is a fairly frequent event that may occur spontaneously or may be the …

Clinical relevance of hepatitis B viral mutations

CM Hunt, JM McGill, MI Allen, LD Condreay - Hepatology, 2000 - journals.lww.com
One third of the global population has been acutely infected with hepatitis B virus (HBV);
less than 1% of patients with acute infection will develop fulminant hepatitis. 1 Approximately …

[HTML][HTML] Occult hepatitis B virus infection in patients with chronic hepatitis C liver disease

I Cacciola, T Pollicino, G Squadrito… - … England Journal of …, 1999 - Mass Medical Soc
Background Hepatitis B virus (HBV) infections in patients who lack detectable hepatitis B
surface antigen (HBsAg) are called occult infections. Although such infections have been …

High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases

BF Chen, CJ Liu, GM Jow, PJ Chen, JH Kao, DS Chen - Gastroenterology, 2006 - Elsevier
Background & Aims: The interactions among pre-S deletion, precore (PC) mutation, and
basal core promoter (BCP) mutation in various stages of chronic hepatitis B virus (HBV) …

Genetic variability of the S gene of hepatitis B virus: clinical and diagnostic impact

B Weber - Journal of clinical virology, 2005 - Elsevier
The genetic variability of hepatitis B virus (HBV) represents a challenge for the sensitivity of
immunologic and molecular based assays. Based on sequence divergence in the entire …

Pre-S deletion and complex mutations of hepatitis B virus related to advanced liver disease in HBeAg-negative patients

CH Chen, CH Hung, CM Lee, TH Hu, JH Wang… - Gastroenterology, 2007 - Elsevier
Background & Aims: This longitudinal study investigated the interactions and roles of
hepatitis B virus (HBV) genotypes, pre-S deletions, and core promoter and precore …

[HTML][HTML] Pathogenesis of hepatitis B virus infection

TF Baumert, R Thimme… - World journal of …, 2007 - ncbi.nlm.nih.gov
Infection with hepatitis B virus (HBV) leads to a wide spectrum of clinical presentations
ranging from an asymptomatic carrier state to self-limited acute or fulminant hepatitis to …

Naturally occurring variants of hepatitis B virus

S Günther, L Fischer, I Pult, M Sterneck, H Will - Advances in virus research, 1999 - Elsevier
Publisher Summary Although most living biological systems have developed intricate
mechanisms to keep the genetic information stable, many viruses, including hepatitis B virus …

Vaccine-and hepatitis B immune globulin-induced escape mutations of hepatitis B virus surface antigen

MP Cooreman, G Leroux-Roels, WP Paulij - Journal of biomedical science, 2001 - Springer
Hepatitis B virus surface antigen (HBsAg) vaccination has been shown to be effective in
preventing hepatitis B virus (HBV) infection. The protection is based on the induction of anti …

Quantification of large and middle proteins of hepatitis B virus surface antigen (HBsAg) as a novel tool for the identification of inactive HBV carriers

M Pfefferkorn, S Böhm, T Schott, D Deichsel… - Gut, 2018 - gut.bmj.com
Objective Among individuals with chronic hepatitis B, those with hepatitis B e-antigen
(HBeAg)-negative chronic hepatitis (CHB) can be difficult to distinguish from those with …