One of the most remarkable aspects of an animal's behavior is the ability to modify that
behavior by learning, an ability that reaches its highest form in human beings. For me …

Aging is associated with specific impairments of learning and memory, some of which are
similar to those caused by hippocampal damage. Studies of the effects of aging on …

N-methyl-d-aspartate receptors (NMDARs) in the rodent hippocampus have been shown to
be essential for spatial learning and memory, and for the induction of long-term synaptic …

The hippocampal formation is critical for the acquisition and consolidation of memories.
When recorded in freely moving animals, hippocampal pyramidal neurons fire in a location …

The hypothesis that synaptic plasticity is a critical component of the neural mechanisms
underlying learning and memory is now widely accepted. In this article, we begin by …

NOBEL LECTURE: The Molecular Biology of Memory Storage: A Dialog Between Genes and
Synapses Page 1 Bioscience Reports, Vol. 21, No. 5, October 2001 ( 2002) NOBEL LECTURE …

The heterotrimeric G protein Gs couples hormone receptors (as well as other receptors) to
the effector enzyme adenylyl cyclase and is therefore required for hormone-stimulated …

The hippocampus is responsible for encoding behavioral episodes into short-term and long-
term memory. The circuits that mediate these processes are subject to neuromodulation …

Protein kinases critically regulate synaptic plasticity in the mammalian hippocampus. Cyclic-
AMP dependent protein kinase (PKA) is a serine–threonine kinase that has been strongly …

We recorded hippocampal place cells in two spatial environments: a training environment in
which rats underwent fear conditioning and a neutral control environment. Fear conditioning …