Chronic obstructive pulmonary disease (COPD) is a deadly and highly morbid disease.
Susceptibility to and heterogeneity of COPD are incompletely explained by environmental …

Network medicine is an emerging area of research dealing with molecular and genetic
interactions, network biomarkers of disease, and therapeutic target discovery. Large-scale …

Although chronic obstructive pulmonary disease (COPD) risk is strongly influenced by
cigarette smoking, genetic factors are also important determinants of COPD. In addition to …

Epigenetic mechanisms represent potential molecular routes which could bridge the gap
between genetic background and environmental risk factors contributing to the …

Advanced phenotyping of cardiovascular diseases has evolved with the application of high-
resolution omics screening to populations enrolled in large-scale observational and clinical …

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality
worldwide. COPD heterogeneity has hampered progress in developing pharmacotherapies …

The ability to identify and characterize not only the protein-protein interactions but also their
internal modular organization through network analysis is fundamental for understanding …

Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous syndrome.
Network-based analysis implemented by SWIM software can be exploited to identify key …

Background Chronic obstructive pulmonary disease (COPD) is a leading cause of death in
adults that may have origins in early lung development. It is a complex disease, influenced …

The molecular and clinical features of a complex disease can be influenced by other
diseases affecting the same individual. Understanding disease-disease interactions is …