Monoamine oxidases (MAO-A and MAO-B) are mammalian flavoenzyme, which catalyze the
oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine …

Monoamine oxidase enzyme is necessary for the management of brain functions. It
oxidatively metabolizes monoamines and produces ammonia, aldehyde and hydrogen …

Due to their pharmacological importance in the oxidation of amine neurotransmitters, the
membrane-bound flavoenzymes monoamine oxidase A and monoamine oxidase B have …

Monoamine oxidase (MAO) inhibitors have made significant contributions and remain an
indispensable approach of molecular and mechanistic diversity for the discovery of …

The enzyme-catalyzed degradation of the biogenic amine serotonin is an essential
regulatory mechanism of its level in the human organism. In particular, monoamine oxidase …

Monoamine oxidase (MAO, EC. 1.4. 3.4) has been a drug target for 60 years, with the
primary rationale of developing drugs to treat neuropsychiatric disorders. The biological …

Current structural results of several flavin-dependent amine oxidizing enzymes including
human monoamine oxidases A and B (MAO A and MAO B) show aromatic amino acid …

The work provides a new model for the prediction of the MAO-A and-B inhibitor activity by
the use of combined complex networks and QSAR methodologies. On the basis of the …

Monoamine oxidases (MAOs) are flavoenzymes important in regulating amine
neurotransmitter levels and are the central pharmacological targets in treating depression …

The flavoenzyme monoamine oxidase (MAO) is essential for the enzymatic decomposition of
neurotransmitters. While it is commonly accepted that the rate limiting step of the reaction is …