The evolution of metabolic pathways is a major force behind natural selection. In the
spotlight of such process lies the structural evolution of the enzymatic machinery responsible …

Several decades after the discovery of the first antibiotic (penicillin) microbes have evolved
novel mechanisms of resistance; endangering not only our abilities to combat future …

ADP-glucose pyrophosphorylase (AGPase) catalyzes the rate-limiting step of bacterial
glycogen and plant starch biosynthesis, the most common carbon storage polysaccharides …

New 2-arylquinazoline benzamide derivatives were synthesized and screened against
H37RV strain, compounds displayed specific and potent anti-mycobacterial activity against …

Methicillin-resistant Staphylococcus aureus (MRSA) is a leading threat to public health as it
is resistant to most currently available antibiotics. Prodigiosin is a secondary metabolite of …

ADP-glucose pyrophosphorylase (AGPase) controls bacterial glycogen and plant starch
biosynthetic pathways, the most common carbon storage polysaccharides in nature …

On screening of endolithic actinobacteria from a granite rock sample of Meghalaya for
antibacterial compound, a novel antibacterial compound CCp1 was isolated from the …

Bacterial infections are a major cause of mortality and morbidity in humans throughout the
world. Infections due to resistant bacterial strains such as methicillin-resistant …

Glycogen and starch are the major carbon and energy reserve polysaccharides in nature,
providing living organisms with a survival advantage. The evolution of the enzymatic …

Shigellosis remains a worldwide health problem due to the lack of vaccines and the
emergence of antibiotic-resistant strains. Shigella (S.) dysenteriae has rigid peptidoglycan …