Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C (ut) annabinoid” System

KF Tóth, D Ádám, T Bíró, A Oláh - Molecules, 2019 - mdpi.com
The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

[图书][B] Melatoninergic system in the skin

AT Slominski, MA Zmijewski, C Skobowiat, B Zbytek… - 2012 - Springer
Melatonin production is highly conserved in nature through different species including
bacteria, unicellular eukaryotes, algae, plants invertebrates, and vertebrates (Hardeland et …

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

A Oláh, BI Tóth, I Borbíró, K Sugawara… - The Journal of …, 2014 - Am Soc Clin Investig
The endocannabinoid system (ECS) regulates multiple physiological processes, including
cutaneous cell growth and differentiation. Here, we explored the effects of the major …

Therapeutic potential of cannabidiol (CBD) for skin health and disorders

SM Baswan, AE Klosner, K Glynn… - Clinical, cosmetic and …, 2020 - Taylor & Francis
Though there is limited research confirming the purported topical benefits of cannabinoids, it
is certain that cutaneous biology is modulated by the human endocannabinoid system …

Is lipid signaling through cannabinoid 2 receptors part of a protective system?

P Pacher, R Mechoulam - Progress in lipid research, 2011 - Elsevier
The mammalian body has a highly developed immune system which guards against
continuous invading protein attacks and aims at preventing, attenuating or repairing the …

The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities

T Bíró, BI Tóth, G Haskó, R Paus, P Pacher - Trends in pharmacological …, 2009 - cell.com
The newly discovered endocannabinoid system (ECS; comprising the endogenous lipid
mediators endocannabinoids present in virtually all tissues, their G-protein-coupled …

Human hair follicle organ culture: theory, application and perspectives

EA Langan, MP Philpott, JE Kloepper… - Experimental …, 2015 - Wiley Online Library
For almost a quarter of a century, ex vivo studies of human scalp hair follicles (HF s) have
permitted major advances in hair research, spanning diverse fields such as chronobiology …

The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders

C Del Río, E Millan, V Garcia, G Appendino… - Biochemical …, 2018 - Elsevier
The skin is the largest organ of the body and has a complex and very active structure that
contributes to homeostasis and provides the first line defense against injury and infection. In …

Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor‐2‐mediated signaling

N Dobrosi, BI Tóth, G Nagy, A Dózsa… - The FASEB …, 2008 - Wiley Online Library
We had previously shown that both locally produced endocannabinoids and
exocannabinoids, via cannabinoid receptor‐1 (CB1), are powerful inhibitors of human hair …

Cannabinoids and inflammations of the gut-lung-skin barrier

C Scheau, C Caruntu, IA Badarau, AE Scheau… - Journal of Personalized …, 2021 - mdpi.com
Recent studies have identified great similarities and interferences between the epithelial
layers of the digestive tract, the airways and the cutaneous layer. The relationship between …