Nutrition and metabolism modify epigenetic signatures like histone acetylation and DNA
methylation. Histone acetylation and DNA methylation in the central nervous system (CNS) …

This review delves into the intricate relationship between excess folate (vitamin B9) intake,
especially its synthetic form, namely, folic acid, and its implications on health and disease …

Background The capacity of a polyphenol-enriched diet to modulate the epigenome in vivo
is partly unknown. Given the beneficial metabolic effects of a Mediterranean (MED) diet …

Prenatal alcohol consumption (PAE) may be associated with a broad spectrum of impacts,
ranging from no overt effects, to miscarriage, fetal growth restriction and fetal alcohol …

The PI3K/AKT/mTOR signaling pathway may play crucial roles in the pathogenesis of
obesity and diabetes mellitus, as well as metabolic syndromes, which could also be risk …

Folate, also known as vitamin B9, facilitates the transfer of methyl groups among molecules,
which is crucial for amino acid metabolism and nucleotide synthesis. Adequate maternal …

Obesity is a complex multifactorial condition that often manifests in early life with a lifelong
burden on metabolic health. Diet, including pre-pregnancy maternal diet, in utero nutrition …

Corneal diseases are among the primary causes of blindness and vision loss worldwide.
However, the pathogenesis of corneal diseases remains elusive, and diagnostic and …

Suboptimal status of folate and/or interrelated B vitamins (B12, B6 and riboflavin) can
perturb one‐carbon metabolism and adversely affect brain development in early life and …

Background Antenatal micronutrient supplementation has been defined as a priority for Low-
and Middle-income Countries (LMICs). However, it is also relevant to assess its performance …