Abstract Purpose of Review Delayed cerebral ischemia (DCI) is common after subarachnoid
hemorrhage (SAH) and represents a significant cause of poor functional outcome. DCI was …

Aneurysmal subarachnoid haemorrhage is a neurological syndrome with complex systemic
complications. The rupture of an intracranial aneurysm leads to the acute extravasation of …

Subarachnoid hemorrhage (SAH) can lead to devastating neurological outcomes, and there
are few pharmacologic treatments available for treating this condition. Both animal and …

Abstract Significance: Haptoglobin (Hp) is an abundant human plasma protein that tightly
captures hemoglobin (Hb) during hemolysis. The Hb-Hp complex formation reduces the …

Haemoglobin is released into the CNS during the breakdown of red blood cells after
intracranial bleeding. Extracellular free haemoglobin is directly neurotoxic. Haemoglobin …

Aneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological
disorders, with a high mortality rate and severe disabling functional sequelae. Systemic …

Subarachnoid hemorrhage (SAH) is an important cause of stroke mortality and morbidity,
especially in the young stroke population. Recent evidences indicate that neuroinflammation …

In Brief Prospective identification of individuals with diabetes who are at greatest risk for
developing complications would have considerable public health importance by allowing …

The mechanisms underlying poor outcome following subarachnoid haemorrhage (SAH) are
complex and multifactorial. They include early brain injury, spreading depolarisation …

Cerebral vasospasm (CV) and the resulting delayed cerebral ischemia (DCI) significantly
contribute to poor outcomes following aneurysmal subarachnoid hemorrhage (aSAH). Free …