Stem cells and common biomaterials in dentistry: a review study

SA Mosaddad, B Rasoolzade, RA Namanloo… - Journal of Materials …, 2022 - Springer
Stem cells exist as normal cells in embryonic and adult tissues. In recent years, scientists
have spared efforts to determine the role of stem cells in treating many diseases. Stem cells …

[HTML][HTML] Transplantation of photoreceptors into the degenerative retina: Current state and future perspectives

SJ Gasparini, S Llonch, O Borsch, M Ader - Progress in retinal and eye …, 2019 - Elsevier
The mammalian retina displays no intrinsic regenerative capacities, therefore retinal
degenerative diseases such as age-related macular degeneration (AMD) or retinitis …

Functional dissection of the enhancer repertoire in human embryonic stem cells

TS Barakat, F Halbritter, M Zhang, AF Rendeiro… - Cell stem cell, 2018 - cell.com
Enhancers are genetic elements that regulate spatiotemporal gene expression. Enhancer
function requires transcription factor (TF) binding and correlates with histone modifications …

Human pluripotent stem cell culture: current status, challenges, and advancement

S Dakhore, B Nayer, K Hasegawa - Stem cells international, 2018 - Wiley Online Library
Over the past two decades, human embryonic stem cells (hESCs) have gained attention due
to their pluripotent and proliferative ability which enables production of almost all cell types …

N6‐methyladenosine‐modified DBT alleviates lipid accumulation and inhibits tumor progression in clear cell renal cell carcinoma through the ANXA2/YAP axis …

D Miao, Q Wang, J Shi, Q Lv, D Tan… - Cancer …, 2023 - Wiley Online Library
Background The mechanism of metabolism reprogramming is an unsolved problem in clear
cell renal cell carcinoma (ccRCC). Recently, it was discovered that the Hippo pathway …

The many faces of Pluripotency: in vitro adaptations of a continuum of in vivo states

S Morgani, J Nichols, AK Hadjantonakis - BMC developmental biology, 2017 - Springer
Pluripotency defines the propensity of a cell to differentiate into, and generate, all somatic,
as well as germ cells. The epiblast of the early mammalian embryo is the founder population …

Mapping human pluripotent stem cell differentiation pathways using high throughput single-cell RNA-sequencing

X Han, H Chen, D Huang, H Chen, L Fei, C Cheng… - Genome biology, 2018 - Springer
Background Human pluripotent stem cells (hPSCs) provide powerful models for studying
cellular differentiations and unlimited sources of cells for regenerative medicine. However, a …

Direct generation of human naive induced pluripotent stem cells from somatic cells in microfluidics

S Giulitti, M Pellegrini, I Zorzan, P Martini… - Nature cell …, 2019 - nature.com
Induced pluripotent stem cells (iPSCs) are generated via the expression of the transcription
factors OCT4 (also known as POU5F1), SOX2, KLF4 and cMYC (OSKM) in somatic cells. In …

[PDF][PDF] Two decades of embryonic stem cells: a historical overview

C Eguizabal, B Aran… - Human …, 2019 - academic.oup.com
STUDY QUESTION How did the field of stem cell research develop in the years following the
derivation of the first human embryonic stem cell (hESC) line? SUMMARY ANSWER …

Esrrb, an estrogen‐related receptor involved in early development, pluripotency, and reprogramming

N Festuccia, N Owens, P Navarro - FEBS letters, 2018 - Wiley Online Library
Estrogen‐related receptor b (Esrrb) is part of a family of three orphan nuclear receptors with
broad expression profiles and a generic function in regulating energy metabolism in …