Abstract (C–X–C motif) ligand (CXCL) 10 (CXCL10) belongs to the ELR− CXC subfamily
chemokine. CXCL10 exerts its function through binding to chemokine (C–X–C motif) …

Chemokines, binding their various G protein-coupled receptors, lead the way for leukocytes
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes …

Systemic sclerosis (SSc) is a complex, multiorgan, autoimmune disease. Lung fibrosis
occurs in∼ 80% of patients with SSc; 25% to 30% develop progressive interstitial lung …

Background Plasmacytoid dendritic cells have been implicated in the pathogenesis of
systemic sclerosis through mechanisms beyond the previously suggested production of type …

Abstract Introduction Systemic sclerosis (SSc) is an autoimmune connective tissue disorder
characterized by fibroproliferative vasculopathy, immunological abnormalities and …

Systemic sclerosis (SSc), also known as scleroderma, is a rare connective tissue disease
characterized by vascular and immune dysfunction, leading to fibrosis that can damage …

CXCL10 is a 10 kDa protein, which is categorized functionally as a Th1-chemokine. It binds
to the receptor CXCR3 and regulates immune responses through the activation and …

Biomarkers have the potential to become central to the clinical evaluation and monitoring of
patients with chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype …

Systemic sclerosis (SSc) has the highest cause-specific mortality of all the connective tissue
diseases, and the aetiology of this complex and heterogeneous condition remains an …

Objective Mikulicz disease has been considered to be a subtype of Sjögren's syndrome
(SS). However, recent studies have suggested that Mikulicz disease is an IgG4‐related …