Giant virus biology and diversity in the era of genome-resolved metagenomics

F Schulz, C Abergel, T Woyke - Nature Reviews Microbiology, 2022 - nature.com
The discovery of giant viruses, with capsids as large as some bacteria, megabase-range
genomes and a variety of traits typically found only in cellular organisms, was one of the …

Acanthamoeba, an environmental phagocyte enhancing survival and transmission of human pathogens

B Rayamajhee, MDP Willcox, FL Henriquez… - Trends in …, 2022 - cell.com
The opportunistic protist Acanthamoeba, which interacts with other microbes such as
bacteria, fungi, and viruses, shows significant similarity in cellular and functional aspects to …

[HTML][HTML] Dynamic genome evolution and complex virocell metabolism of globally-distributed giant viruses

M Moniruzzaman, CA Martinez-Gutierrez… - Nature …, 2020 - nature.com
The discovery of eukaryotic giant viruses has transformed our understanding of the limits of
viral complexity, but the extent of their encoded metabolic diversity remains unclear. Here …

[HTML][HTML] Microbial culturomics: paradigm shift in the human gut microbiome study

JC Lagier, F Armougom, M Million, P Hugon… - Clinical Microbiology …, 2012 - Elsevier
Comprehensive determination of the microbial composition of the gut microbiota and the
relationships with health and disease are major challenges in the 21st century …

In-depth study of Mollivirus sibericum, a new 30,000-y-old giant virus infecting Acanthamoeba

M Legendre, A Lartigue, L Bertaux… - Proceedings of the …, 2015 - National Acad Sciences
Acanthamoeba species are infected by the largest known DNA viruses. These include
icosahedral Mimiviruses, amphora-shaped Pandoraviruses, and Pithovirus sibericum, the …

The rapidly expanding universe of giant viruses: Mimivirus, Pandoravirus, Pithovirus and Mollivirus

C Abergel, M Legendre… - FEMS microbiology …, 2015 - academic.oup.com
More than a century ago, the term 'virus' was introduced to describe infectious agents that
are invisible by light microscopy and capable of passing through sterilizing filters. In addition …

Medusavirus, a novel large DNA virus discovered from hot spring water

G Yoshikawa, R Blanc-Mathieu, C Song… - Journal of …, 2019 - Am Soc Microbiol
Recent discoveries of new large DNA viruses reveal high diversity in their morphologies,
genetic repertoires, and replication strategies. Here, we report the novel features of …

[HTML][HTML] Virus-encoded histone doublets are essential and form nucleosome-like structures

Y Liu, H Bisio, CM Toner, S Jeudy, N Philippe, K Zhou… - Cell, 2021 - cell.com
The organization of genomic DNA into defined nucleosomes has long been viewed as a
hallmark of eukaryotes. This paradigm has been challenged by the identification of" …

“Megavirales”, a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses

P Colson, X De Lamballerie, N Yutin, S Asgari… - Archives of …, 2013 - Springer
The nucleocytoplasmic large DNA viruses (NCLDVs) comprise a monophyletic group of
viruses that infect animals and diverse unicellular eukaryotes. The NCLDV group includes …

Exploring nucleo-cytoplasmic large DNA viruses in Tara Oceans microbial metagenomes

P Hingamp, N Grimsley, SG Acinas, C Clerissi… - The ISME …, 2013 - academic.oup.com
Nucleo-cytoplasmic large DNA viruses (NCLDVs) constitute a group of eukaryotic viruses
that can have crucial ecological roles in the sea by accelerating the turnover of their …