Going back to the biology of FGF21: new insights
JE Lewis, FJP Ebling, RJ Samms, K Tsintzas - Trends in Endocrinology & …, 2019 - cell.com
Fibroblast growth factor 21 (FGF21) is a protein highly synthesized in the liver that exerts
paracrine and endocrine control of many aspects of energy homeostasis in multiple tissues …
paracrine and endocrine control of many aspects of energy homeostasis in multiple tissues …
VGF as a biomarker and therapeutic target in neurodegenerative and psychiatric diseases
JP Quinn, SE Kandigian, BA Trombetta… - Brain …, 2021 - academic.oup.com
Neurosecretory protein VGF (non-acronymic) belongs to the granin family of neuropeptides.
VGF and VGF-derived peptides have been repeatedly identified in well-powered and well …
VGF and VGF-derived peptides have been repeatedly identified in well-powered and well …
Exercise training in obese rats does not induce browning at thermoneutrality and induces a muscle-like signature in brown adipose tissue
Aim: Exercise training elicits diverse effects on brown (BAT) and white adipose tissue (WAT)
physiology in rodents housed below their thermoneutral zone (ie, 28–32° C). In these …
physiology in rodents housed below their thermoneutral zone (ie, 28–32° C). In these …
An integrative view of mammalian seasonal neuroendocrinology
Seasonal neuroendocrine cycles that govern annual changes in reproductive activity,
energy metabolism and hair growth are almost ubiquitous in mammals that have evolved at …
energy metabolism and hair growth are almost ubiquitous in mammals that have evolved at …
VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice
F El Gaamouch, M Audrain, WJ Lin… - Molecular …, 2020 - Springer
Background Multiomic studies by several groups in the NIH Accelerating Medicines
Partnership for Alzheimer's Disease (AMP-AD) identified VGF as a major driver of …
Partnership for Alzheimer's Disease (AMP-AD) identified VGF as a major driver of …
Biocompatible exosome-modified fibrin gel accelerates the recovery of spinal cord injury by VGF-mediated oligodendrogenesis
X He, L Yang, K Dong, F Zhang, Y Liu, B Ma… - Journal of …, 2022 - Springer
Exosomes show potential for treating patients with spinal cord injury (SCI) in clinical
practice, but the underlying repair mechanisms remain poorly understood, and biological …
practice, but the underlying repair mechanisms remain poorly understood, and biological …
Genome-wide association study of body weight traits in chinese fine-wool sheep
Z Lu, Y Yue, C Yuan, J Liu, Z Chen, C Niu, X Sun… - Animals, 2020 - mdpi.com
Simple Summary Body weight traits are economically important in the sheep industry, and it
is critical to explore their underlying genetic architecture. Hence, four body weight traits …
is critical to explore their underlying genetic architecture. Hence, four body weight traits …
Neural programming of seasonal physiology in birds and mammals: a modular perspective
TJ Stevenson, TA Liddle, C Stewart, CJ Marshall… - Hormones and …, 2022 - Elsevier
Most animals in the temperate zone exhibit robust seasonal rhythms in neuroendocrine,
physiological and behavioral processes. The integration of predictive and supplementary …
physiological and behavioral processes. The integration of predictive and supplementary …
Prenatal social support in low-risk pregnancy shapes placental epigenome
Background Poor social support during pregnancy has been linked to inflammation and
adverse pregnancy and childhood health outcomes. Placental epigenetic alterations may …
adverse pregnancy and childhood health outcomes. Placental epigenetic alterations may …
[HTML][HTML] VGF: A prospective biomarker and therapeutic target for neuroendocrine and nervous system disorders
Y Wang, X Qin, Y Han, B Li - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Neuroendocrine regulatory polypeptide VGF (nerve growth factor inducible) was firstly found
in the rapid induction of nerve growth factor on PC12 cells. It was selectively distributed in …
in the rapid induction of nerve growth factor on PC12 cells. It was selectively distributed in …