International consensus statement on allergy and rhinology: rhinosinusitis 2021

RR Orlandi, TT Kingdom, TL Smith… - International forum of …, 2021 - Wiley Online Library
I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

[HTML][HTML] Zinc and respiratory tract infections: Perspectives for COVID‑19

AV Skalny, L Rink, OP Ajsuvakova… - International …, 2020 - spandidos-publications.com
In view of the emerging COVID‑19 pandemic caused by SARS‑CoV‑2 virus, the search for
potential protective and therapeutic antiviral strategies is of particular and urgent interest …

SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance

R Robinot, M Hubert, GD de Melo, F Lazarini… - Nature …, 2021 - nature.com
Understanding how SARS-CoV-2 spreads within the respiratory tract is important to define
the parameters controlling the severity of COVID-19. Here we examine the functional and …

Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells

N Zhu, W Wang, Z Liu, C Liang, W Wang, F Ye… - Nature …, 2020 - nature.com
Abstract SARS-CoV-2, a β-coronavirus, has rapidly spread across the world, highlighting its
high transmissibility, but the underlying morphogenesis and pathogenesis remain poorly …

First contact: the role of respiratory cilia in host-pathogen interactions in the airways

LE Kuek, RJ Lee - … Journal of Physiology-Lung Cellular and …, 2020 - journals.physiology.org
Respiratory cilia are the driving force of the mucociliary escalator, working in conjunction
with secreted airway mucus to clear inhaled debris and pathogens from the conducting …

Modified cyclodextrins as broad-spectrum antivirals

ST Jones, V Cagno, M Janeček, D Ortiz, N Gasilova… - Science …, 2020 - science.org
Viral infections kill millions of people and new antivirals are needed. Nontoxic drugs that
irreversibly inhibit viruses (virucidal) are postulated to be ideal. Unfortunately, all virucidal …

Cytoskeleton—a crucial key in host cell for coronavirus infection

Z Wen, Y Zhang, Z Lin, K Shi… - Journal of molecular cell …, 2020 - academic.oup.com
The emerging coronavirus (CoV) pandemic is threatening the public health all over the
world. Cytoskeleton is an intricate network involved in controlling cell shape, cargo transport …

Proteome profiling of recombinant DNase therapy in reducing NETs and aiding recovery in COVID-19 patients

J Fisher, T Mohanty, CAQ Karlsson… - Molecular & Cellular …, 2021 - ASBMB
Severe coronavirus disease 2019 (COVID-19) can result in pneumonia and acute
respiratory failure. Accumulation of mucus in the airways is a hallmark of the disease and …

A machine-generated view of the role of blood glucose levels in the severity of COVID-19

E Logette, C Lorin, C Favreau, E Oshurko… - Frontiers in Public …, 2021 - frontiersin.org
SARS-CoV-2 started spreading toward the end of 2019 causing COVID-19, a disease that
reached pandemic proportions among the human population within months. The reasons for …

Sequential infections with rhinovirus and influenza modulate the replicative capacity of SARS-CoV-2 in the upper respiratory tract

M Essaidi-Laziosi, C Alvarez, O Puhach… - Emerging Microbes & …, 2022 - Taylor & Francis
Although frequently reported since the beginning of the pandemic, questions remain
regarding the impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) …