Integration of GC–MS and LC–MS for untargeted metabolomics profiling
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …
scientific community as it is applied in several researches relating to diseases diagnosis …
Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies
MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …
developments in molecular analysis, which include important advances in instrumental …
Global metabolic profiling procedures for urine using UPLC–MS
The production of'global'metabolite profiles involves measuring low molecular-weight
metabolites (< 1 kDa) in complex biofluids/tissues to study perturbations in response to …
metabolites (< 1 kDa) in complex biofluids/tissues to study perturbations in response to …
Mass spectrometric based approaches in urine metabolomics and biomarker discovery
Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
Pre-analytical factors that affect metabolite stability in human urine, plasma, and serum: a review
VL Stevens, E Hoover, Y Wang, KA Zanetti - Metabolites, 2019 - mdpi.com
Metabolomics provides a comprehensive assessment of numerous small molecules in
biological samples. As it integrates the effects of exogenous exposures, endogenous …
biological samples. As it integrates the effects of exogenous exposures, endogenous …
Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research
Mass spectrometry (MS) techniques, because of their sensitivity and selectivity, have
become methods of choice to characterize the human metabolome and MS-based …
become methods of choice to characterize the human metabolome and MS-based …
Quantitative metabolomics using NMR
DS Wishart - TrAC trends in analytical chemistry, 2008 - Elsevier
Nuclear magnetic resonance (NMR) spectroscopy can be used to both identify and quantify
chemicals from complex mixtures. This can be done semi-automatically by comparing the …
chemicals from complex mixtures. This can be done semi-automatically by comparing the …
Recommendations and best practices for standardizing the pre-analytical processing of blood and urine samples in metabolomics
R González-Domínguez, Á González-Domínguez… - Metabolites, 2020 - mdpi.com
Metabolomics can be significantly influenced by a range of pre-analytical factors, such as
sample collection, pre-processing, aliquoting, transport, storage and thawing. This therefore …
sample collection, pre-processing, aliquoting, transport, storage and thawing. This therefore …
Computational and statistical analysis of metabolomics data
Metabolomics is the comprehensive study of small molecule metabolites in biological
systems. By assaying and analyzing thousands of metabolites in biological samples, it …
systems. By assaying and analyzing thousands of metabolites in biological samples, it …
NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations
Metabolomics is a dynamic and emerging research field, similar to proteomics,
transcriptomics and genomics in affording global understanding of biological systems. It is …
transcriptomics and genomics in affording global understanding of biological systems. It is …