Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …

Phenolic compounds in plants are essential components of human nutrition, which provide
various health benefits. However, some missing links became the research in phenolic …

α-Synuclein (α-syn) is a presynaptic protein that regulates the release of neurotransmitters
from synaptic vesicles in the brain. α-Syn aggregates, including Lewy bodies, are features of …

The amyloid aggregation of α-synuclein (α-Syn) is highly associated with Parkinson's
disease (PD). Discovering α-Syn amyloid inhibitors is one of the strategies for PD therapies …

Cyclodextrins, representing a versatile family of cyclic oligosaccharides, have extensive
pharmaceutical applications due to their unique truncated cone-shaped structure with a …

The study of human movement and biomechanics forms an integral part of various clinical
assessments and provides valuable information toward diagnosing neurodegenerative …

Coronavirus disease-19 (COVID-19) emerged in December 2019 and quickly spread, giving
rise to a pandemic crisis. Therefore, it triggered tireless efforts to identify the mechanisms of …

Autophagy is a process of degradation of macromolecules in the cytoplasm, particularly
proteins of a long half-life, as well as whole organelles, in eukaryotic cells. Lysosomes play …

The accumulation of protein aggregates in human tissues is a hallmark of more than 40
diseases called amyloidoses. In seven of these disorders, the aggregation is associated with …

Increasing epidemiological and experimental evidence has demonstrated an inverse
relationship between the consumption of plant foods and the incidence of chronic diseases …