Blood–brain barrier (BBB) strictly controls matter exchange between blood and brain, and
severely limits brain penetration of systemically administered drugs, resulting in ineffective …

Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …

This review summarizes articles that have been reported in literature on liposome-based
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …

Beyond the emerging field of oncological ultrasound molecular imaging, the recent
significant advancements in ultrasound and contrast agent technology have paved the way …

Background Therapy for glioblastoma (GBM) has always been very challenging, not only
because of the presence of the blood-brain barrier (BBB) but also due to susceptibility to …

Glioblastoma multiforme (GBM) is a neurologically debilitating disease that culminates in
death 14 to 16 months after diagnosis. An incomplete understanding of how cataloged …

Recent advances in maximum safe glioma resection have included the introduction of a host
of visualization techniques to complement intraoperative white-light imaging of tumors …

Existing drug delivery methods have not led to a significant increase in survival for patients
with malignant primary brain tumors. While the combination of conventional therapies …

Glioma is still hard to be treated due to their complex microenvironment. In this study, a gold
nanoparticle-based delivery system was developed. The system, An-PEG-DOX-AuNPs, was …

Nanosuspensions, as a new drug delivery system for insoluble drugs, are only composed of
a drug and a small amount of stabilizer, which is dispersed in an aqueous solution with high …