Defining success with HIV pre-exposure prophylaxis: a prevention-effective adherence paradigm

JE Haberer, DR Bangsberg, JM Baeten, K Curran… - Aids, 2015 - journals.lww.com
To date, six clinical trials have explored the efficacy of pre-exposure prophylaxis (PrEP)
against HIV infection using oral tenofovir and/or emtricitabine/tenofovir [1–6]. Efficacy ranged …

Interventions to increase antiretroviral adherence in sub-Saharan Africa: a systematic review of evaluation studies

T Bärnighausen, K Chaiyachati… - The Lancet infectious …, 2011 - thelancet.com
The success of potent antiretroviral treatment for HIV infection is primarily determined by
adherence. We systematically review the evidence of effectiveness of interventions to …

Adherence to antiretroviral therapy and virologic failure: a meta-analysis

WM Bezabhe, L Chalmers, LR Bereznicki… - Medicine, 2016 - journals.lww.com
Adherence to Antiretroviral Therapy and Virologic Failure: A... : Medicine Adherence to
Antiretroviral Therapy and Virologic Failure: A Meta-Analysis : Medicine Log in or Register …

Text message intervention designs to promote adherence to antiretroviral therapy (ART): a meta-analysis of randomized controlled trials

DJ Finitsis, JA Pellowski, BT Johnson - PloS one, 2014 - journals.plos.org
Background The efficacy of antiretroviral therapy depends on patient adherence to a daily
medication regimen, yet many patients fail to adhere at high enough rates to maintain health …

Adherence to highly active antiretroviral therapy (HAART): a meta-analysis

C Ortego, TB Huedo-Medina, J Llorca, L Sevilla… - AIDS and Behavior, 2011 - Springer
This meta-analysis synthesizes eighty-four observational studies, conducted across twenty
countries, to determine the mean proportion of people who reported≥ 90% adherence to …

How complexity science can inform scale-up and spread in health care: understanding the role of self-organization in variation across local contexts

HJ Lanham, LK Leykum, BS Taylor… - Social science & …, 2013 - Elsevier
Health care systems struggle to scale-up and spread effective practices across diverse
settings. Failures in scale-up and spread (SUS) are often attributed to a lack of consideration …

[PDF][PDF] British HIV Association guidelines for the routine investigation and monitoring of adult HIV-1-infected individuals 2011.

D Asboe, C Aitken, M Boffito, C Booth, P Cane… - HIV medicine, 2012 - bhiva.org
In the mid-1990s, the clinical care of patients with HIV infection changed fundamentally as a
result of the development and introduction of effective antiretroviral therapy (ART). This led …

Significance and clinical management of persistent low-level viremia and very-low-level viremia in HIV-1-infected patients

P Ryscavage, S Kelly, JZ Li, PR Harrigan… - Antimicrobial agents …, 2014 - Am Soc Microbiol
ABSTRACT A goal of HIV therapy is to sustain suppression of the plasma viral load below
the detection limits of clinical assays. However, widely followed treatment guidelines diverge …

Women and vulnerability to HAART non-adherence: a literature review of treatment adherence by gender from 2000 to 2011

CM Puskas, JI Forrest, S Parashar, KA Salters… - Current HIV/AIDS …, 2011 - Springer
A literature review of original research articles on adherence to antiretroviral therapy (ART)
in developed countries, covering January 2000 to June 2011, was conducted to determine if …

Suboptimal adherence to combination antiretroviral therapy is associated with higher levels of inflammation despite HIV suppression

JR Castillo-Mancilla, TT Brown… - Clinical Infectious …, 2016 - academic.oup.com
Background Human immunodeficiency virus (HIV)–infected individuals exhibit residual
inflammation regardless of virologic suppression. We evaluated whether suboptimal …