Obesity in children and adolescents: epidemiology, causes, assessment, and management

H Jebeile, AS Kelly, G O'Malley… - The lancet Diabetes & …, 2022 - thelancet.com
This Review describes current knowledge on the epidemiology and causes of child and
adolescent obesity, considerations for assessment, and current management approaches …

Anti-obesity drug discovery: advances and challenges

TD Müller, M Blüher, MH Tschöp… - Nature Reviews Drug …, 2022 - nature.com
Enormous progress has been made in the last half-century in the management of diseases
closely integrated with excess body weight, such as hypertension, adult-onset diabetes and …

Reasons for and consequences of low energy availability in female and male athletes: social environment, adaptations, and prevention

P Wasserfurth, J Palmowski, A Hahn, K Krüger - Sports medicine-open, 2020 - Springer
Low energy availability (LEA) represents a state in which the body does not have enough
energy left to support all physiological functions needed to maintain optimal health. When …

Phentermine/topiramate for the treatment of adolescent obesity

AS Kelly, MO Bensignor, DS Hsia… - NEJM …, 2022 - evidence.nejm.org
Background Antiobesity medication may be useful for the treatment of pediatric obesity, yet
few safe and effective options exist. We evaluated phentermine/topiramate (PHEN/TPM) for …

Fisiopatología de la obesidad: Perspectiva actual

W Suárez-Carmona, AJ Sánchez-Oliver… - Revista chilena de …, 2017 - SciELO Chile
La obesidad es una enfermedad crónica de origen multifactorial, asociada a
complicaciones de salud potencialmente graves, y con una elevada prevalencia a nivel …

Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial

CB Ebbeling, HA Feldman, GL Klein, JMW Wong… - bmj, 2018 - bmj.com
Objective To determine the effects of diets varying in carbohydrate to fat ratio on total energy
expenditure. Design Randomized trial. Setting Multicenter collaboration at US two sites …

Daily caloric restriction limits tumor growth more effectively than caloric cycling regardless of dietary composition

LCD Pomatto-Watson, M Bodogai, O Bosompra… - Nature …, 2021 - nature.com
Cancer incidence increases with age and is a leading cause of death. Caloric restriction
(CR) confers benefits on health and survival and delays cancer. However, due to CR's …

Physiological adaptations to weight loss and factors favouring weight regain

FL Greenway - International journal of obesity, 2015 - nature.com
Obesity is a major global health problem and predisposes individuals to several
comorbidities that can affect life expectancy. Interventions based on lifestyle modification (for …

The weight‐inclusive versus weight‐normative approach to health: evaluating the evidence for prioritizing well‐being over weight loss

TL Tylka, RA Annunziato, D Burgard… - Journal of …, 2014 - Wiley Online Library
Using an ethical lens, this review evaluates two methods of working within patient care and
public health: the weight-normative approach (emphasis on weight and weight loss when …

NIH working group report: innovative research to improve maintenance of weight loss

PS MacLean, RR Wing, T Davidson, L Epstein… - …, 2015 - Wiley Online Library
Objectives The National Institutes of Health, led by the National Heart, Lung, and Blood
Institute, organized a working group of experts to discuss the problem of weight regain after …