Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

Abstract The aluminium-[18F] fluoride ([18F] AlF) radiolabelling method combines the
favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal …

Inert and stable radiolabeling of monoclonal antibodies (mAb), antibody fragments, or
antibody mimetics with radiometals is a prerequisite for immuno-PET. While radiolabeling is …

Immuno-positron emission tomography (immunoPET) is a molecular imaging modality
combining the high sensitivity of PET with the specific targeting ability of monoclonal …

Although radioactive experiments are necessary in radiopharmaceutical drug discovery and
theranostic cancer research, they are expensive, require special facilities, and face certain …

With the aim to efficiently develop and synthesize new radiotracers for PET imaging, and
their use for theranostic approaches, radiolabeling technics have not ceased to progress …

Simple Summary Neuroimaging has transformed the way brain tumors are diagnosed and
treated. Although different non-invasive modalities provide very helpful information, in some …

The concept of positron emission tomography (PET) based imaging was developed more
than 40 years ago. It has been a widely adopted technique for detecting and staging …

In radiopharmaceutical syntheses, maleimide is commonly used for linking thiol-bearing
bioactive molecules to metal–complexing ligands (chelators). However, due to instability of …

Monoclonal antibodies and antibody fragments have proven to be highly effective vectors for
the delivery of radionuclides to target tissues for positron emission tomography (PET) and …