Cyclosporine is one of the most vital agents in the process of successful allogeneic
hematopoietic stem cell transplantation. Despite a long history and worldwide extent of …

The calcineurin inhibitors (CNI s) cyclosporine A (CsA) and tacrolimus (Tac) are
immunosuppressive drugs, which are typically employed in the field of organ …

Background: Kidney transplantation is associated with various biochemical abnormalities
such as changes in serum blood level of sodium (Na), potassium (K), calcium (Ca), and …

Kidney transplantation remains the optimal therapy for many patients with end-stage kidney
disease (ESKD). Chronic pain is one of the most common and distressing symptoms among …

Background: Sox17 is a member of the Sry-related high mobility group (HMG) of
transcription factors that is necessary for endodermal formation and liver development in …

Modelling methods that are commonly used to establish a murine model of hypoxic renal
interstitial fibrosis mainly includes 5/6 nephrectomy, unilateral ureteral obstruction and …

Context: An immunosuppressive drug, Cyclosporine (CsA), has been commonly used in
kidney transplants. A safe dosing of CsA often causes nephrotoxity, bone marrow toxicity …

Heart transplantation (HTx) continues to be the gold standard treatment for patients with
advanced heart failure. Following HTx, patients are placed on a lifelong regimen of …

Cmax didžiausia vaisto koncentracija plazmoje Cvid. vidutinė prognozuojama vaisto
koncentracija plazmoje DIG digitalio tyrinėjimo grupė (angl. Digitalis Investigation Group) …

In their recent large, retrospective, cross-sectional study with 7702 renal-transplant patients,
Einollahi et al. showed that cyclosporine (CsA) absorption (CA) steadily increases over 3 …