[HTML][HTML] The JAK/STAT signaling pathway: from bench to clinic

X Hu, J Li, M Fu, X Zhao, W Wang - Signal transduction and targeted …, 2021 - nature.com
The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling
pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults: A GRADE-assessed systematic review and dose–response meta-analysis of …

MJ Dehzad, H Ghalandari, M Nouri, M Askarpour - Cytokine, 2023 - Elsevier
Turmeric and its prominent bioactive compound, curcumin, have been the subject of many
investigations with regard to their impact on inflammatory and oxidative balance in the body …

Polydatin attenuates cisplatin‐induced acute kidney injury by inhibiting ferroptosis

L Zhou, P Yu, T Wang, Y Du, Y Chen… - Oxidative medicine …, 2022 - Wiley Online Library
Cisplatin is widely used in the treatment of solid tumors, but its application is greatly limited
due to its nephrotoxicity; thus, there is still no effective medicine for the treatment of cisplatin …

[HTML][HTML] Frailty in CKD and transplantation

EC Lorenz, CC Kennedy, AD Rule… - Kidney International …, 2021 - Elsevier
The population is aging. Although older adults have higher rates of comorbidities and
adverse health events, they represent a heterogeneous group with different health …

SIRT1, a promising regulator of bone homeostasis

YE Chen, F Zhou, H Liu, J Li, H Che, J Shen, E Luo - Life Sciences, 2021 - Elsevier
Abstract Sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide-dependent deacetylase,
epigenetically regulates various cell metabolisms, including inflammation, tumorigenesis …

Resveratrol in disease prevention and health promotion: A role of the gut microbiome

X Chen, J Zhang, N Yin, P Wele, F Li… - Critical Reviews in …, 2024 - Taylor & Francis
Resveratrol is a bioactive polyphenolic compound mainly present in grapes and red wine. It
is known to exert beneficial effects in various experimental settings, such as antioxidant, anti …

[HTML][HTML] Caloric restriction induced epigenetic effects on aging

J Zhai, WH Kongsberg, Y Pan, C Hao… - Frontiers in Cell and …, 2023 - frontiersin.org
Aging is the subject of many studies, facilitating the discovery of many interventions.
Epigenetic influences numerous life processes by regulating gene expression and also …

Effects of curcumin/turmeric supplementation on obesity indices and adipokines in adults: A grade‐assessed systematic review and dose–response meta‐analysis of …

MJ Dehzad, H Ghalandari, M Nouri… - Phytotherapy …, 2023 - Wiley Online Library
In the present study, we explored the effect of curcumin/turmeric supplementation on
anthropometric indices of obesity, leptin, and adiponectin. We searched PubMed, Scopus …

[HTML][HTML] Ferroptosis: a new mechanism of traditional Chinese medicine compounds for treating acute kidney injury

Y Shi, X Shi, M Zhao, M Chang, S Ma… - Biomedicine & …, 2023 - Elsevier
Acute kidney injury (AKI) is a major health concern owing to its high morbidity and mortality
rates, to which there are no drugs or treatment methods, except for renal replacement …