Molecularly imprinted polymers-based DNA biosensors

N Nawaz, NKA Bakar, HNME Mahmud… - Analytical …, 2021 - Elsevier
In multiple biological processes, molecular recognition performs an integral role in detecting
bio analytes. Molecular imprinted polymers (MIPs) are tailored sensing materials that can …

Isothermal exponential amplification techniques: from basic principles to applications in electrochemical biosensors

H Qi, S Yue, S Bi, C Ding, W Song - Biosensors and Bioelectronics, 2018 - Elsevier
As a conventional amplification technique, polymerase chain reaction (PCR) has been
widely applied to detect a variety of analytes with exponential amplification efficiency …

Sensitive and selective DNA detecting electrochemical sensor via double cleaving CRISPR Cas12a and dual polymerization on hyperbranched rolling circle …

J You, H Park, H Lee, K Jang, J Park, S Na - Biosensors and Bioelectronics, 2023 - Elsevier
Electrochemical sensors are widely used for nucleic acid detection. However, they exhibit
low sensitivity and specificity. To overcome these limitations, DNA amplification method is …

Aptamer recognition-trigged label-free homogeneous electrochemical strategy for an ultrasensitive cancer-derived exosome assay

X Yin, T Hou, B Huang, L Yang, F Li - Chemical Communications, 2019 - pubs.rsc.org
Aptamer recognition-trigged label-free homogeneous electrochemical strategy for an
ultrasensitive cancer-derived exosome assay - Chemical Communications (RSC Publishing) …

Homogeneous electrochemical detection of ochratoxin A in foodstuff using aptamer–graphene oxide nanosheets and DNase I-based target recycling reaction

AL Sun, YF Zhang, GP Sun, XN Wang… - Biosensors and …, 2017 - Elsevier
A simple and feasible homogeneous electrochemical sensing protocol was developed for
the detection of ochratoxin A (OTA) in foodstuff on the immobilization-free aptamer …

Homogeneous electrochemical strategy for human telomerase activity assay at single-cell level based on T7 exonuclease-aided target recycling amplification

X Liu, W Li, T Hou, S Dong, G Yu, F Li - Analytical chemistry, 2015 - ACS Publications
As an important biomarker for early cancer diagnostics and a valuable therapeutic target,
telomerase has attracted extensive attention concerning its detection and monitoring …

Electrochemical detection of miRNA combining T7 exonuclease-assisted cascade signal amplification and DNA-templated copper nanoparticles

P Miao, T Zhang, J Xu, Y Tang - Analytical chemistry, 2018 - ACS Publications
miRNA has been serving as an ideal biomarker for diagnosis, prognosis, and therapy of
many severe diseases. In this study, we have developed an amplified electrochemical …

Biphasic photoelectrochemical sensing strategy based on in situ formation of CdS quantum dots for highly sensitive detection of acetylcholinesterase activity and …

T Hou, L Zhang, X Sun, F Li - Biosensors and Bioelectronics, 2016 - Elsevier
Herein, we reported a facile and highly sensitive biphasic photoelectrochemical (PEC)
sensing strategy based on enzymatic product-mediated in situ formation of CdS quantum …

Affinity-mediated homogeneous electrochemical aptasensor on a graphene platform for ultrasensitive biomolecule detection via exonuclease-assisted target-analog …

L Ge, W Wang, X Sun, T Hou, F Li - Analytical chemistry, 2016 - ACS Publications
As is well-known, graphene shows a remarkable difference in affinity toward nonstructured
single-stranded (ss) DNA and double-stranded (ds) DNA. This property makes it popular to …

Design of nuclease-based target recycling signal amplification in aptasensors

M Yan, W Bai, C Zhu, Y Huang, J Yan… - Biosensors and …, 2016 - Elsevier
Compared with conventional antibody-based immunoassay methods, aptasensors based on
nucleic acid aptamer have made at least two significant breakthroughs. One is that aptamers …