The yin and yang of human soil-transmitted helminth infections
The major soil-transmitted helminths that infect humans are the roundworms, whipworms
and hookworms. Soil-transmitted helminth infections rank among the most important …
and hookworms. Soil-transmitted helminth infections rank among the most important …
Metabolomics and lipidomics studies of parasitic helminths: molecular diversity and identification levels achieved by using different characterisation tools
Introduction Helminths are parasitic worms that infect millions of people worldwide and
secrete a variety of excretory-secretory products (ESPs), including proteins, peptides, and …
secrete a variety of excretory-secretory products (ESPs), including proteins, peptides, and …
A genome-scale metabolic model of parasitic whipworm
Genome-scale metabolic models are widely used to enhance our understanding of
metabolic features of organisms, host-pathogen interactions and to identify therapeutics for …
metabolic features of organisms, host-pathogen interactions and to identify therapeutics for …
The interplay between Trichuris and the microbiota
Parasitic worms are amongst the most common pathogens to infect humans and have a long-
established history of inflicting disease in their hosts. There is a large body of evidence that …
established history of inflicting disease in their hosts. There is a large body of evidence that …
Immunomodulatory and biological properties of helminth-derived small molecules: Potential applications in diagnostics and therapeutics
Parasitic helminths secrete and excrete a vast array of molecules known to help skew or
suppress the host's immune response, thereby establishing a niche for sustained parasite …
suppress the host's immune response, thereby establishing a niche for sustained parasite …
High-fat feeding drives the intestinal production and assembly of C16:0 ceramides in chylomicrons
Consumption of a diet rich in saturated fat increases lipid absorption from the intestine,
assembly into chylomicrons, and delivery to metabolic tissues via the lymphatic and …
assembly into chylomicrons, and delivery to metabolic tissues via the lymphatic and …
How to train your myeloid cells: a way forward for helminth vaccines?
R Doolan, N Putananickal, L Tritten… - Frontiers in …, 2023 - frontiersin.org
Soil-transmitted helminths affect approximately 1.5 billion people worldwide. However, as no
vaccine is currently available for humans, the current strategy for elimination as a public …
vaccine is currently available for humans, the current strategy for elimination as a public …
Untargeted Multimodal Metabolomics Investigation of the Haemonchus contortus Exsheathment Secretome
N Palevich, PH Maclean, PM Candy, W Taylor… - Cells, 2022 - mdpi.com
In nematodes that invade the gastro-intestinal tract of the ruminant, the process of larval
exsheathment marks the transition from the free-living to the parasitic stages of these …
exsheathment marks the transition from the free-living to the parasitic stages of these …
Enteric tuft cells in host-parasite interactions
Enteric tuft cells are chemosensory epithelial cells gaining attention in the field of host-
parasite interactions. Expressing a repertoire of chemosensing receptors and mediators …
parasite interactions. Expressing a repertoire of chemosensing receptors and mediators …
A multi‐omics analysis for the prediction of neurocognitive disorders risk among the elderly in Macao
Background Due to the increasing ageing population, neurocognitive disorders (NCDs)
have been a global public health issue, and its prevention and early diagnosis are crucial …
have been a global public health issue, and its prevention and early diagnosis are crucial …