[HTML][HTML] An overview of oxidative stress, neuroinflammation, and neurodegenerative diseases

DM Teleanu, AG Niculescu, II Lungu, CI Radu… - International journal of …, 2022 - mdpi.com
Oxidative stress has been linked with a variety of diseases, being involved in the debut
and/or progress of several neurodegenerative disorders. This review intends to summarize …

[HTML][HTML] Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis

SU Khan, AN Lone, MS Khan, SS Virani… - …, 2021 - thelancet.com
Background The effects of omega-3 fatty acids (FAs), such as eicosapentaenoic (EPA) and
docosahexaenoic (DHA) acids, on cardiovascular outcomes are uncertain. We aimed to …

Omega‐3 fatty acids for the primary and secondary prevention of cardiovascular disease

AS Abdelhamid, TJ Brown, JS Brainard… - Cochrane Database …, 2018 - cochranelibrary.com
Background Researchers have suggested that omega‐3 polyunsaturated fatty acids from
oily fish (long‐chain omega‐3 (LCn3), including eicosapentaenoic acid (EPA) and …

Ferroptosis as a mechanism of neurodegeneration in Alzheimer's disease

M Jakaria, AA Belaidi, AI Bush… - Journal of …, 2021 - Wiley Online Library
Alzheimer's disease (AD) is the most prevalent form of dementia, with complex
pathophysiology that is not fully understood. While β‐amyloid plaque and neurofibrillary …

The metal ion hypothesis of Alzheimer's disease and the anti-neuroinflammatory effect of metal chelators

LL Chen, YG Fan, LX Zhao, Q Zhang, ZY Wang - Bioorganic chemistry, 2023 - Elsevier
Abstract Alzheimer's disease (AD), characterized by the β-amyloid protein (Aβ) deposition
and tau hyperphosphorylation, is the most common dementia with uncertain etiology. The …

[HTML][HTML] Involvement of lipids in Alzheimer's disease pathology and potential therapies

H Chew, VA Solomon, AN Fonteh - Frontiers in physiology, 2020 - frontiersin.org
Lipids constitute the bulk of the dry mass of the brain and have been associated with healthy
function as well as the most common pathological conditions of the brain. Demographic …

Screening for cognitive impairment in older adults: updated evidence report and systematic review for the US Preventive Services Task Force

CD Patnode, LA Perdue, RC Rossom, MC Rushkin… - Jama, 2020 - jamanetwork.com
Importance Early identification of cognitive impairment may improve patient and caregiver
health outcomes. Objective To systematically review the test accuracy of cognitive screening …

Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease

F Pistollato, S Sumalla Cano, I Elio… - Nutrition …, 2016 - academic.oup.com
It has been hypothesized that alterations in the composition of the gut microbiota might be
associated with the onset of certain human pathologies, such as Alzheimer disease, a …

[HTML][HTML] Oxidative stress in neurodegenerative diseases

E Niedzielska, I Smaga, M Gawlik, A Moniczewski… - Molecular …, 2016 - Springer
The pathophysiologies of neurodegenerative diseases, including amyotrophic lateral
sclerosis (ALS), Parkinson's disease (PD), and Alzheimer's disease (AD), are far from being …

Targeting oxidative stress mechanisms to treat Alzheimer's and Parkinson's disease: a critical review

AT Aborode, M Pustake, WA Awuah… - Oxidative medicine …, 2022 - Wiley Online Library
Neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson's disease
(PD) are becoming more frequent as the age increases. Contemporary therapies provide …