Antigen‐specific immunotherapy of cervical and ovarian cancer

CF Hung, TC Wu, A Monie, R Roden - Immunological reviews, 2008 - Wiley Online Library
We contrast the efforts to treat ovarian cancer and cervical cancer through vaccination
because of their different pathobiology. A plethora of approaches have been developed for …

Therapeutic human papillomavirus vaccines: current clinical trials and future directions

CF Hung, B Ma, A Monie, SW Tsen… - Expert opinion on …, 2008 - Taylor & Francis
Background: Cervical cancer is the second largest cause of cancer deaths in women
worldwide. It is now evident that persistent infection with high-risk human papillomavirus …

Nanog signaling in cancer promotes stem-like phenotype and immune evasion

KH Noh, BW Kim, KH Song, H Cho… - The Journal of …, 2012 - Am Soc Clin Investig
Adaptation of tumor cells to the host is a major cause of cancer progression, failure of
therapy, and ultimately death. Immune selection drives this adaptation in human cancer by …

Perspectives for preventive and therapeutic HPV vaccines

K Lin, K Doolan, CF Hung, TC Wu - Journal of the Formosan Medical …, 2010 - Elsevier
Human Papillomavirus (HPV) has been associated with several human cancers, including
cervical cancer, vulvar cancer, vaginal and anal cancer, and a subset of head and neck …

Therapeutic hpv DNA vaccines

K Lin, E Roosinovich, B Ma, CF Hung, TC Wu - Immunologic research, 2010 - Springer
It is now well established that most cervical cancers are causally associated with HPV
infection. This realization has led to efforts to control HPV-associated malignancy through …

Immunotherapy for cervical cancer: Research status and clinical potential

JH Su, A Wu, E Scotney, B Ma, A Monie, CF Hung… - BioDrugs, 2010 - Springer
The high-risk types of human papillomavirus (HPV) have been found to be associated with
most cervical cancers and play an essential role in the pathogenesis of the disease. Despite …

Therapeutic DNA vaccines for human papillomavirus and associated diseases

MA Cheng, E Farmer, C Huang, J Lin, CF Hung… - Human gene …, 2018 - liebertpub.com
Human papillomavirus (HPV) has long been recognized as the causative agent of cervical
cancer. High-risk HPV types 16 and 18 alone are responsible for over 70% of all cases of …

Targeted treatments for cervical cancer: a review

O Peralta-Zaragoza, VH Bermúdez-Morales… - OncoTargets and …, 2012 - Taylor & Francis
Cervical cancer is the second most common cause of cancer death in women worldwide
and the development of new diagnosis, prognostic, and treatment strategies merits special …

Flagellin enhances tumor-specific CD8+ T cell immune responses through TLR5 stimulation in a therapeutic cancer vaccine model

CT Nguyen, SH Hong, JI Sin, HVD Vu, K Jeong… - Vaccine, 2013 - Elsevier
Tumor antigen (TA)-specific immunotherapy is an emerging approach for cancer treatment.
Potent adjuvants are prerequisites to the immunotherapy for overcoming the low …

Antigen‐specific cytotoxic T lymphocytes protect against lethal West Nile virus encephalitis

WE Purtha, N Myers, V Mitaksov, E Sitati… - European journal of …, 2007 - Wiley Online Library
Abstract Infection with West Nile virus (WNV) causes fatal encephalitis in
immunocompromised animals. Previous studies in mice have established that T cell …