Dysregulation of long noncoding RNA (lncRNA) expression is linked to the development of
various diseases. Recently, an emerging body of evidence has indicated that lncRNAs play …

Long noncoding RNA (lncRNA) has recently been investigated as key modulators that
regulate many biological processes in human cancers via diverse mechanisms. LncRNAs …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the colonic mucosa.
Environmental factors, genetics, intestinal microbiota, and the immune system are all …

The classic understanding of molecular disease-mechanisms is largely based on protein-
centric models. During the past decade however, genetic studies have identified numerous …

This study reveals a previously uncharacterized mechanism to restrict intestinal
inflammation via a regulatory RNA transcribed from a noncoding genomic locus. We …

Long non-coding RNA (lncRNA) is a non-coding RNA which lacks a complete open reading
frame (ORF) and plays an important role in biological processes such as cell proliferation …

There is a huge number of noncoding RNA (ncRNA) transcripts in the cell with important
roles in modulation of different mechanisms. ANRIL is a long ncRNA with 3.8 kb length that …

The innate immune system relies on a germ-line-encoded repertoire of pattern recognition
receptors (PRRs), activated by deeply conserved pathogen signatures, such as bacterial cell …

Accumulating evidence has revealed that aberrantly expressed long non-coding transcripts
are involved in the development and progression of colorectal cancer (CRC). Small …