Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Emerging autologous cellular therapies that utilize platelet-rich plasma (PRP) applications
have the potential to play adjunctive roles in a variety of regenerative medicine treatment …

Importance Most clinical guidelines do not recommend platelet-rich plasma (PRP) for knee
osteoarthritis (OA) because of lack of high-quality evidence on efficacy for symptoms and …

Polysaccharide hydrogels have been widely utilized in tissue engineering. They interact with
the organismal environments, modulating the cargos release and realizing of long-term …

Knee osteoarthritis (KOA) represents a clinical challenge due to poor potential for
spontaneous healing of cartilage lesions. Several treatment options are available for KOA …

Osteoarthritis (OA) is a degenerative multifactorial disease with concomitant structural,
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …

Background This study aimed to evaluate the clinical efficacy of platelet-rich plasma (PRP)
injection compared with hyaluronic acid (HA) injection for patients undergoing knee …

Background: Bone marrow aspirate concentrate (BMAC) has emerged as a therapeutic
option for symptomatic knee osteoarthritis (OA). Purpose: To systematically review the …

Osteoarthritis is the most common musculoskeletal progressive disease, with the knee as
the most commonly affected joint in the human body. While several new medications are still …

Background: In younger patients and those without severe degenerative changes, the
efficacy of intra-articular (IA) injections as a nonoperative modality for treating symptomatic …