Reversal learning paradigms are among the most widely used tests of cognitive flexibility
and have been used as assays, across species, for altered cognitive processes in a host of …

People with damage to the orbitofrontal cortex (OFC) have specific problems making
decisions, whereas their other cognitive functions are spared. Neurophysiological studies …

The number of papers about the orbitofrontal cortex (OFC) has grown from 1 per month in
1987 to a current rate of over 50 per month. This publication stream has implicated the OFC …

Orbitofrontal cortex (OFC) has long been known to play an important role in decision
making. However, the exact nature of that role has remained elusive. Here, we propose a …

Successful goal-directed behavior requires not only correct action selection, planning, and
execution but also the ability to flexibly adapt behavior when performance problems occur or …

Rat orbitofrontal cortex (OFC) is located in the dorsal bank of the rhinal sulcus, and is
divided into the medial orbital area, ventral orbital area, ventrolateral orbital area, lateral …

The orbitofrontal cortex (OFC) has long been associated with the flexible control of behavior
and concepts such as behavioral inhibition, self-control, and emotional regulation. These …

Two ideas have dominated neuropsychology concerning the orbitofrontal cortex (OFC). One
holds that OFC regulates emotion and enhances behavioral flexibility through inhibitory …

Rationale Dopamine neurotransmission has long been known to exert a powerful influence
over the vigor, strength, or rate of responding. However, there exists no clear understanding …

The orbitofrontal cortex (OFC) is crucial for changing established behaviour in the face of
unexpected outcomes. This function has been attributed to the role of the OFC in response …