Advances in our understanding of the intricate molecular mechanisms for transformation of a
normal cell to a cancer cell, and the aberrant control of complementary pathways, have …

Over the last 10 years there has been an explosion of information about the molecular
biology of cancer. A challenge in oncology is to translate this information into advances in …

Simple Summary Despite tremendous efforts in finding new therapeutic strategies and
promoting screening programs to increase early diagnosis, breast cancer is still a major …

Major depressive disorder (MDD) and bipolar disorder (BD) lack robust biomarkers useful
for screening purposes in a clinical setting. A systematic review of the literature was …

Molecular therapies targeting HER2 are part of the established drug armamentarium in
breast carcinoma. Now the ToGA trial, an international multicenter phase III clinical study …

Accurate determination of human epidermal growth factor receptor 2 (HER2) expression is
essential for HER2-targeted therapy in patients with cancer. HER2 expression in a complex …

The term P4 medicine is used to denote an evolving field of medicine that uses systems
biology approaches and information technologies to enhance wellness rather than just treat …

Since its discovery, the human epidermal growth factor 2 (HER2) has been extensively
studied. Presently, there are 2 standard diagnostic techniques to assess HER2 status in …

Background Human epidermal growth factor receptor 2 (HER2) expression status
determination significantly contributes to HER2-targeted therapy in breast cancer (BC). The …

Abstract● Introduction● Methods for proteomic analysis–Sample fractionation/biochemical
fractionation–MS● The cholesterol system–Cholesterol and apolipoproteins–Cholesterol …