[HTML][HTML] What is a cell type and how to define it?
H Zeng - Cell, 2022 - cell.com
Cell types are the basic functional units of an organism. Cell types exhibit diverse
phenotypic properties at multiple levels, making them challenging to define, categorize, and …
phenotypic properties at multiple levels, making them challenging to define, categorize, and …
Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease
In the past decade, single-cell technologies have proliferated and improved from their
technically challenging beginnings to become common laboratory methods capable of …
technically challenging beginnings to become common laboratory methods capable of …
[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …
types with specific spatial distribution patterns and structural and functional properties …
Specialized astrocytes mediate glutamatergic gliotransmission in the CNS
Multimodal astrocyte–neuron communications govern brain circuitry assembly and function.
For example, through rapid glutamate release, astrocytes can control excitability, plasticity …
For example, through rapid glutamate release, astrocytes can control excitability, plasticity …
Comparative cellular analysis of motor cortex in human, marmoset and mouse
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally
conserved across mammals. Here, using high-throughput transcriptomic and epigenomic …
conserved across mammals. Here, using high-throughput transcriptomic and epigenomic …
A multimodal cell census and atlas of the mammalian primary motor cortex
Principal manuscript editors, Analysis coordination… - Nature, 2021 - nature.com
Here we report the generation of a multimodal cell census and atlas of the mammalian
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …
Morphological diversity of single neurons in molecularly defined cell types
Dendritic and axonal morphology reflects the input and output of neurons and is a defining
feature of neuronal types,, yet our knowledge of its diversity remains limited. Here, to …
feature of neuronal types,, yet our knowledge of its diversity remains limited. Here, to …
Human neocortical expansion involves glutamatergic neuron diversification
The neocortex is disproportionately expanded in human compared with mouse,, both in its
total volume relative to subcortical structures and in the proportion occupied by …
total volume relative to subcortical structures and in the proportion occupied by …
Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex
Elucidating the cellular organization of the cerebral cortex is critical for understanding brain
structure and function. Using large-scale single-nucleus RNA sequencing and spatial …
structure and function. Using large-scale single-nucleus RNA sequencing and spatial …
[HTML][HTML] A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation
The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in
perception, cognition, emotion, and learning. We profiled∼ 1.3 million cells covering the …
perception, cognition, emotion, and learning. We profiled∼ 1.3 million cells covering the …