Structured models of ontogenic, phenotypic and functional diversity have been instrumental
for a renewed understanding of the biology of immune cells, such as macrophages and …

Neutrophils, the most abundant human immune cells, are rapidly recruited to sites of
infection, where they fulfill their life-saving antimicrobial functions. While traditionally …

Microglia-mediated neuroinflammation has been implicated in the pathogenesis of
Alzheimer's disease (AD). Although microglia in aging and neurodegenerative disease …

Severe congenital neutropenias are a heterogeneous group of rare haematological
diseases characterized by impaired maturation of neutrophil granulocytes. Patients with …

Neutrophils are produced in the bone marrow from stem cells that proliferate and
differentiate to mature neutrophils fully equipped with an armory of granules. These contain …

Neutrophils, the most abundant white blood cells in human circulation, entertain intense
interactions with other leukocyte subsets, platelets, and stromal cells. Molecularly, such …

Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

Alzheimer's disease (AD) is the most common form of dementia, pathologically
characterized by senile plaques and neurofibrillary tangles (NFTs), resulting in …

WNT proteins are secreted morphogens that are required for basic developmental
processes, such as cell-fate specification, progenitor-cell proliferation and the control of …

Neutrophils are phagocytes whose principal function is to maintain anti-bacterial immunity.
Neutrophils ingest and kill invading bacteria, releasing cytotoxic, chemotactic and …