Is Cannabis a boon or bane? Cannabis sativa has long been a versatile crop for fiber
extraction (industrial hemp), traditional Chinese medicine (hemp seeds), and recreational …

Butylphthalide is one of the first-line drugs for ischemic stroke therapy, while no biosynthetic
enzyme for butylphthalide has been reported. Here, we present a haplotype-resolved …

Nicotiana benthamiana is a model plant, widely used for research. The susceptibility of
young plants to Agrobacterium tumefaciens has been utilised for transient gene expression …

In the decades since the first cannabinoids were identified by scientists, research has
focused almost exclusively on the function and capacity of cannabinoids as medicines and …

CBG (Cannabigerol), a nonpsychoactive cannabinoid, has garnered attention due to its
extensive antimicrobial and anti‐inflammatory properties. However, the natural content of …

Trema, a genus of the popularly known Cannabaceae, has recently been the subject of
cannabinoid bioprospection. T. micrantha is a tree with pharmacological potential widely …

Mitochondrial cytochrome c maturation (CCM) requires heme attachment via distinct
pathways termed systems I and III. The mosaic distribution of these systems in …

Phytocannabinoids are natural products with highly interesting pharmacological properties
mainly produced by plants. The production of cannabinoids in a heterologous host system …

The huge structural diversity exhibited by plant specialized metabolites has primarily been
considered to result from the catalytic specificity of their biosynthetic enzymes. Accordingly …

Yeast metabolism can be engineered to produce xenobiotic compounds, such as
cannabinoids, the principal isoprenoids of the plant Cannabis sativa, through heterologous …