Anorexia nervosa and the immune system—a narrative review

D Gibson, PS Mehler - Journal of clinical medicine, 2019 - mdpi.com
The pathogenesis of an increasing number of chronic diseases is being attributed to effects
of the immune system. However, its role in the development and maintenance of anorexia …

Anorexia nervosa: Gut microbiota-immune-brain interactions

R Roubalová, P Procházková, H Papežová, K Smitka… - Clinical Nutrition, 2020 - Elsevier
Anorexia nervosa is a psychiatric disorder defined by an extremely low body weight, a
devastating fear of weight gain, and body image disturbance, however the etiopathogenesis …

[HTML][HTML] On the origin of eating disorders: altered signaling between gut microbiota, adaptive immunity and the brain melanocortin system regulating feeding behavior

SO Fetissov, T Hökfelt - Current Opinion in Pharmacology, 2019 - Elsevier
Research in the field of gut microbiota–brain axis may contribute to clarifying the origin of
anorexia nervosa and bulimia, the two principal forms of eating disorders (ED). The initial …

[HTML][HTML] Epigenetics of functional hypothalamic amenorrhea

L Fontana, E Garzia, G Marfia, V Galiano… - Frontiers in …, 2022 - frontiersin.org
Functional hypothalamic amenorrhea (FHA) is a temporary infertility characterized by the
suppression of the hypothalamic–pituitary–gonadal (HPG) axis, induced by the inhibition of …

Eating disorders, heredity and environmental activation: getting epigenetic concepts into practice

H Steiger, L Booij - Journal of clinical medicine, 2020 - mdpi.com
Epigenetic mechanisms are believed to link environmental exposures to alterations in gene
expression, and in so doing, to provide a physical substrate for the activation of hereditary …

Immunoinflammatory processes: Overlapping mechanisms between obesity and eating disorders?

E Breton, JF Soh, L Booij - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Obesity and eating disorders are conditions that involve eating behaviors and are
sometimes comorbid. Current evidence supports alterations in immunoinflammatory …

Genetic risk factors for eating disorders: an update and insights into pathophysiology

H Himmerich, J Bentley, C Kan… - Therapeutic advances …, 2019 - journals.sagepub.com
Genome-wide-association studies (GWASs), epigenetic, gene-expression and gene–gene
interaction projects, nutritional genomics and investigations of the gut microbiota have …

Genetic contributions to the etiology of anorexia nervosa: New perspectives in molecular diagnosis and treatment

S Paolacci, AK Kiani, E Manara… - Molecular genetics & …, 2020 - Wiley Online Library
Background Anorexia nervosa is a multifactorial eating disorder that manifests with self‐
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …

An evolutionary genetic perspective of eating disorders

AJ Mayhew, M Pigeyre, J Couturier, D Meyre - Neuroendocrinology, 2018 - karger.com
Eating disorders (ED) including anorexia nervosa (AN), bulimia nervosa (BN), and binge
eating disorder (BED) affect up to 5% of the population in Western countries. Risk factors for …

Stressful life events among individuals with a history of eating disorders: a case-control comparison

SØ Lie, CM Bulik, OA Andreassen, Ø Rø, L Bang - BMC psychiatry, 2021 - Springer
Background Experiencing stressful life events (SLEs) can negatively impact mental health
and increase risk for psychiatric disorders including eating disorders (EDs). Previous …