[HTML][HTML] Epstein–Barr virus in multiple sclerosis: theory and emerging immunotherapies
New treatments for multiple sclerosis (MS) focused on B cells have created an atmosphere
of excitement in the MS community. B cells are now known to play a major role in disease …
of excitement in the MS community. B cells are now known to play a major role in disease …
Treatment of multiple sclerosis—success from bench to bedside
M Tintore, A Vidal-Jordana… - Nature Reviews …, 2019 - nature.com
The modern era of multiple sclerosis (MS) treatment began 25 years ago, with the approval
of IFNβ and glatiramer acetate for the treatment of relapsing–remitting MS. Ten years later …
of IFNβ and glatiramer acetate for the treatment of relapsing–remitting MS. Ten years later …
[HTML][HTML] Mesenchymal stromal cell apoptosis is required for their therapeutic function
Multipotent mesenchymal stromal cells (MSCs) ameliorate a wide range of diseases in
preclinical models, but the lack of clarity around their mechanisms of action has impeded …
preclinical models, but the lack of clarity around their mechanisms of action has impeded …
Beneficial effects of autologous mesenchymal stem cell transplantation in active progressive multiple sclerosis
In this study (trial registration: NCT02166021), we aimed to evaluate the optimal way of
administration, the safety and the clinical efficacy of mesenchymal stem cell (MSC) …
administration, the safety and the clinical efficacy of mesenchymal stem cell (MSC) …
[HTML][HTML] Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019
Background The causes for immune-mediated inflammatory diseases (IMIDs) are diverse
and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to …
and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to …
[HTML][HTML] Autologous haematopoietic stem cell transplantation and other cellular therapy in multiple sclerosis and immune-mediated neurological diseases: updated …
B Sharrack, R Saccardi, T Alexander… - Bone marrow …, 2020 - nature.com
These updated EBMT guidelines review the clinical evidence, registry activity and
mechanisms of action of haematopoietic stem cell transplantation (HSCT) in multiple …
mechanisms of action of haematopoietic stem cell transplantation (HSCT) in multiple …
[HTML][HTML] Promoting remyelination in multiple sclerosis
N Cunniffe, A Coles - Journal of neurology, 2021 - Springer
The greatest unmet need in multiple sclerosis (MS) are treatments that delay, prevent or
reverse progression. One of the most tractable strategies to achieve this is to therapeutically …
reverse progression. One of the most tractable strategies to achieve this is to therapeutically …
Triboelectric nanogenerators for cellular bioelectrical stimulation
W Zhang, G Li, B Wang, Q Zhu, L Zeng… - Advanced Functional …, 2022 - Wiley Online Library
Triboelectric nanogenerators (TENGs) are an efficient state‐of‐the‐art kinetic energy‐
harvesting technology based on the combination of triboelectrification and electrostatic …
harvesting technology based on the combination of triboelectrification and electrostatic …
Chemical activation of the Piezo1 channel drives mesenchymal stem cell migration via inducing ATP release and activation of P2 receptor purinergic signaling
In this study, we examined the Ca2+-permeable Piezo1 channel, a newly identified
mechanosensing ion channel, in human dental pulp-derived mesenchymal stem cells …
mechanosensing ion channel, in human dental pulp-derived mesenchymal stem cells …
[HTML][HTML] The importance of HLA assessment in “off-the-shelf” allogeneic mesenchymal stem cells based-therapies
M Kot, M Baj-Krzyworzeka, R Szatanek… - International Journal of …, 2019 - mdpi.com
The need for more effective therapies of chronic and acute diseases has led to the attempts
of developing more adequate and less invasive treatment methods. Regenerative medicine …
of developing more adequate and less invasive treatment methods. Regenerative medicine …