Isolation, separation, and preconcentration of biologically active compounds from plant matrices by extraction techniques

V Raks, H Al-Suod, B Buszewski - Chromatographia, 2018 - Springer
Abstract Development of efficient methods for isolation and separation of biologically active
compounds remains an important challenge for researchers. Designing systems such as …

A review of the role of inositols in conditions of insulin dysregulation and in uncomplicated and pathological pregnancy

OC Watkins, HEJ Yong, N Sharma… - Critical Reviews in Food …, 2022 - Taylor & Francis
Inositols, a group of 6-carbon polyols, are highly bioactive molecules derived from diet and
endogenous synthesis. Inositols and their derivatives are involved in glucose and lipid …

Alterations of GABAA and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy

EA Kharlamov, E Lepsveridze, M Meparishvili… - Epilepsy research, 2011 - Elsevier
Traumatic brain injury (TBI) can result in the development of posttraumatic epilepsy (PTE).
Recently, we reported differential alterations in tonic and phasic GABAA receptor (GABAAR) …

Tipping the scales: Lessons from simple model systems on inositol imbalance in neurological disorders

AD Frej, GP Otto, RSB Williams - European journal of cell biology, 2017 - Elsevier
Inositol and inositol-containing compounds have signalling and regulatory roles in many
cellular processes, suggesting that inositol imbalance may lead to wide-ranging changes in …

An aqueous extract of Syzygium cumini protects against kainate-induced status epilepticus and amnesia: evidence for antioxidant and anti-inflammatory intervention

AK Kandeda, S Nodeina, ST Mabou - Metabolic Brain Disease, 2022 - Springer
Temporal lobe epilepsy is the most common drug-resistant epilepsy. To cure epilepsy, drugs
must target the mechanisms at the origin of seizures. Thus, the present investigation aimed …

Expression of the AMPA receptor subunits GluR1 and GluR2 is associated with granule cell maturation in the dentate gyrus

H Hagihara, K Ohira, K Toyama… - Frontiers in …, 2011 - frontiersin.org
The dentate gyrus produces new granule neurons throughout adulthood in mammals from
rodents to humans. During granule cell maturation, defined markers are expressed in a …

Isolation and Identification of Myo-Inositol Crystals from Dragon Fruit (Hylocereus polyrhizus)

OPS Rebecca, AN Boyce, C Somasundram - Molecules, 2012 - mdpi.com
Crystals isolated from Hylocereus polyrhizus were analyzed using four different approaches—
X-ray Crystallography, High Performance Liquid Chromatography (HPLC), Liquid …

Fast separation and determination of free myo-inositol by hydrophilic liquid chromatography

J Pazourek - Carbohydrate research, 2014 - Elsevier
A fast liquid chromatography method for separation and determination of myo-inositol is
reported. Determination of the biologically important isomer of inositols, myo-inositol, was …

[HTML][HTML] Anticonvulsant activities of myo-inositol and scyllo-inositol on pentylenetetrazol induced seizures

M Nozadze, E Mikautadze, E Lepsveridze, E Mikeladze… - Seizure, 2011 - Elsevier
Myo-inositol (MI) and its isomers are used for the treatment of various neuropathological
conditions. The purpose of the present research was to study anticonvulsant properties of MI …

Long‐term effects of myoinositol on behavioural seizures and biochemical changes evoked by kainic acid induced epileptogenesis

L Tsverava, M Kandashvili… - Biomed Research …, 2019 - Wiley Online Library
Epilepsy is one of the most devastating neurological diseases and despite significant efforts
there is no cure available. Occurrence of spontaneous seizures in epilepsy is preceded by …