Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasion

SJ Dando, A Mackay-Sim, R Norton… - Clinical microbiology …, 2014 - Am Soc Microbiol
The brain is well protected against microbial invasion by cellular barriers, such as the blood-
brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In addition, cells …

Mechanisms of blood brain barrier disruption by different types of bacteria, and bacterial–host interactions facilitate the bacterial pathogen invading the brain

MMJ Al-Obaidi, MNM Desa - Cellular and molecular neurobiology, 2018 - Springer
This review aims to elucidate the different mechanisms of blood brain barrier (BBB)
disruption that may occur due to invasion by different types of bacteria, as well as to show …

The surface protein HvgA mediates group B streptococcus hypervirulence and meningeal tropism in neonates

A Tazi, O Disson, S Bellais, A Bouaboud… - Journal of experimental …, 2010 - rupress.org
Streptococcus agalactiae (group B streptococcus; GBS) is a normal constituent of the
intestinal microflora and the major cause of human neonatal meningitis. A single clone, GBS …

Similarities and differences in the glycosylation mechanisms in prokaryotes and eukaryotes

A Dell, A Galadari, F Sastre… - International journal of …, 2010 - Wiley Online Library
Recent years have witnessed a rapid growth in the number and diversity of prokaryotic
proteins shown to carry N‐and/or O‐glycans, with protein glycosylation now considered as …

[PDF][PDF] Group B streptococcal infections

MS Edwards, V Nizet, CJ Baker - GROUP, 2006 - researchgate.net
Late-Onset Infection 440 Late Late-Onset Infection 441 Septic Arthritis and Osteomyelitis
441 Cellulitis or Adenitis 441 Unusual Manifestations of Infection 442 Relapse or …

A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta

C Whidbey, MI Harrell, K Burnside, L Ngo… - Journal of Experimental …, 2013 - rupress.org
Microbial infection of the amniotic fluid is a significant cause of fetal injury, preterm birth, and
newborn infections. Group B Streptococcus (GBS) is an important human bacterial pathogen …

Membrane vesicle delivery of a streptococcal M protein disrupts the blood–brain barrier by inducing autophagic endothelial cell death

F Pan, M Zhu, Y Liang, C Yuan… - Proceedings of the …, 2023 - National Acad Sciences
M family proteins are critical virulence determinants of Streptococci. Streptococcus equi
subsp. zooepidemicus (SEZ) are Group C streptococci that cause meningitis in animals and …

The Pneumococcal Serine-Rich Repeat Protein Is an Intra-Species Bacterial Adhesin That Promotes Bacterial Aggregation In Vivo and in Biofilms

CJ Sanchez, P Shivshankar, K Stol… - PLoS …, 2010 - journals.plos.org
The Pneumococcal serine-rich repeat protein (PsrP) is a pathogenicity island encoded
adhesin that has been positively correlated with the ability of Streptococcus pneumoniae to …

[HTML][HTML] Glycan recognition at the saliva–oral microbiome interface

BW Cross, S Ruhl - Cellular immunology, 2018 - Elsevier
The mouth is a first critical interface where most potentially harmful substances or pathogens
contact the host environment. Adaptive and innate immune defense mechanisms are …

Multistate, population-based distributions of candidate vaccine targets, clonal complexes, and resistance features of invasive group B streptococci within the United …

L McGee, S Chochua, Z Li, S Mathis… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Group B Streptococcus (GBS) is a leading cause of neonatal sepsis
and meningitis and an important cause of invasive infections in pregnant and nonpregnant …