The plasma separation card as a novel solution for enhancing central laboratory capability for HIV-1 viral load monitoring in limited-access settings

C Kiyaga, C Makoha, I Nkugwa, C Okiira… - PLOS Global Public …, 2023 - journals.plos.org
Measurement of HIV-1 viral load (VL) is essential for monitoring antiretroviral treatment
(ART) efficacy. The preferred specimen type for VL is plasma, but in remote settings where …

HIV-1 pretreatment and acquired antiretroviral drug resistance before tenofovir/lamivudine/dolutegravir (TLD) roll-out in Mozambique

N Ismael, H Gemusse, I Mahumane, O Laurindo… - BMC Infectious …, 2024 - Springer
Abstract Background The World Health Organization (WHO) recommends that HIV treatment
scale-up is accompanied by a robust assessment of drug resistance emergence and …

Assessment of the performance of the plasma separation card for HIV-1 viral load monitoring in South Africa

L Chimoyi, L Hans, M Oladimeji, G Kindra… - Journal of Clinical …, 2024 - Am Soc Microbiol
Scaling up of newer innovations that address the limitations of the dried blood spot and the
logistics of plasma monitoring is needed. We employed a multi-site, cross-sectional …

[HTML][HTML] A validated in-house assay for HIV drug resistance mutation surveillance from dried blood spot specimens

B Neufeld, C Munyuza, A Reimer, R Capiña… - Journal of Virological …, 2024 - Elsevier
Despite increasing scale-up of antiretroviral therapy (ART) coverage, challenges related to
adherence and HIV drug resistance (HIVDR) remain. The high cost of HIVDR surveillance is …