Regulation of endotoxin tolerance and compensatory anti-inflammatory response syndrome by non-coding RNAs
The onset and the termination of innate immune response must be tightly regulated to
maintain homeostasis and prevent excessive inflammation, which can be detrimental to the …
maintain homeostasis and prevent excessive inflammation, which can be detrimental to the …
Epigenetic regulation in sepsis, role in pathophysiology and therapeutic perspective
RB Falcão-Holanda, MKC Brunialti… - Frontiers in …, 2021 - frontiersin.org
Sepsis is characterized by an initial hyperinflammatory response, with intense cell activation
and cytokine storm. In parallel, a prolonged compensatory anti-inflammatory response …
and cytokine storm. In parallel, a prolonged compensatory anti-inflammatory response …
lncRNA MALAT1 accelerates skeletal muscle cell apoptosis and inflammatory response in sepsis by decreasing BRCA1 expression by recruiting EZH2
H Yong, G Wu, J Chen, X Liu, Y Bai, N Tang… - … Therapy-Nucleic Acids, 2020 - cell.com
Sepsis is a serious and elusive syndrome caused by infection, which is accompanied by a
high mortality worldwide. Recent evidence has documented the regulatory role of long non …
high mortality worldwide. Recent evidence has documented the regulatory role of long non …
Silencing of lncRNA MALAT1 prevents inflammatory injury after lung transplant ischemia-reperfusion by downregulation of IL-8 via p300
L Wei, J Li, Z Han, Z Chen, Q Zhang - Molecular Therapy-Nucleic Acids, 2019 - cell.com
Ischemia-reperfusion injury is a common early complication after lung transplantation. It was
reported that long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma …
reported that long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma …
LncRNA GAS5 inhibits miR-579-3p to activate SIRT1/PGC-1α/Nrf2 signaling pathway to reduce cell pyroptosis in sepsis-associated renal injury
H Ling, Q Li, ZP Duan, YJ Wang… - American Journal of …, 2021 - journals.physiology.org
Sepsis is a life-threatening condition that can lead to several organ failures including kidney.
In this study, we investigated the roles of GAS5 and miR-579-3p in regulating cell pyroptosis …
In this study, we investigated the roles of GAS5 and miR-579-3p in regulating cell pyroptosis …
A conserved long noncoding RNA, GAPLINC, modulates the immune response during endotoxic shock
AC Vollmers, S Covarrubias, D Kuang… - Proceedings of the …, 2021 - National Acad Sciences
Recent studies have identified thousands of long noncoding RNAs (lncRNAs) in mammalian
genomes that regulate gene expression in different biological processes. Although lncRNAs …
genomes that regulate gene expression in different biological processes. Although lncRNAs …
Biological network approach for the identification of regulatory long non-coding RNAs associated with metabolic efficiency in cattle
W Nolte, R Weikard, RM Brunner, E Albrecht… - Frontiers in …, 2019 - frontiersin.org
Background: Genomic regions associated with divergent livestock feed efficiency have been
found predominantly outside protein coding sequences. Long non-coding RNAs (lncRNA) …
found predominantly outside protein coding sequences. Long non-coding RNAs (lncRNA) …
Resveratrol alleviates sepsis-induced acute kidney injury by deactivating the lncRNA MALAT1/MiR-205 axis
B Wang, Y Wang, K Xu, Z Zeng, Z Xu, D Yue… - … European Journal of …, 2021 - termedia.pl
Results Resveratrol treatment significantly brought down serum levels of inflammatory
cytokines (ie TNF-, IL-1 and IL-6), kidney function indicators (ie Scr, blood urea nitrogen …
cytokines (ie TNF-, IL-1 and IL-6), kidney function indicators (ie Scr, blood urea nitrogen …
[HTML][HTML] Identification of potential prostate cancer-related pseudogenes based on competitive endogenous RNA network hypothesis
T Jiang, J Guo, Z Hu, M Zhao, Z Gu… - Medical science monitor …, 2018 - ncbi.nlm.nih.gov
Background Long noncoding RNAs (lncRNAs) have been revealed to function as competing
endogenous RNAs (ceRNAs), which can seclude the common microRNAs (miRNAs) and …
endogenous RNAs (ceRNAs), which can seclude the common microRNAs (miRNAs) and …
[HTML][HTML] Long noncoding RNA MALAT1 modulates sepsis-induced cardiac inflammation through the miR-150-5p/NF-κB axis
S Wei, Q Liu - International journal of clinical and experimental …, 2019 - ncbi.nlm.nih.gov
Background: Accumulating evidence shows that long noncoding RNAs (lncRNAs) and
microRNAs (miRNAs) are involved in the sepsis inflammatory response. However, the …
microRNAs (miRNAs) are involved in the sepsis inflammatory response. However, the …