Heterogeneity and excitability of BRAFV600E-induced tumors is determined by Akt/mTOR-signaling state and Trp53-loss

S Cases-Cunillera, KMJ van Loo, J Pitsch… - Neuro …, 2022 - academic.oup.com
Background Developmental brain tumors harboring BRAF V600E somatic mutation are
diverse. Here, we describe molecular factors that determine BRAF V600E-induced tumor …

Parkin, PINK1 and DJ1 as possible modulators of mTOR pathway in ganglioglioma

K Drapalo, J Jozwiak - International Journal of Neuroscience, 2018 - Taylor & Francis
Purpose: Ganglioglioma (GG) is a non-malignant tumor classified as G1 by the WHO.
Although we currently know that the neoplasm may result from the hyperactivity of protein …

Erk activation as a possible mechanism of transformation of subependymal nodule into subependymal giant cell astrocytoma

M Siedlecka, S Szlufik, W Grajkowska… - Folia …, 2015 - termedia.pl
Erk activation as a possible mechanism of transformation of subependymal nodule into
subependymal giant cell astrocytoma Page 1 8 Folia Neuropathologica 2015; 53/1 Original article …

Ganglion cell tumours in the sella turcica in close morphological connection with pituitary adenomas

E Matyja, M Maksymowicz, W Grajkowska… - Folia …, 2015 - termedia.pl
Ganglion cell tumours in the sellar region are uncommon. They are usually associated with
pituitary adenomas, while isolated ganglion cell neoplasms are extremely rare. We report …

Pituitary stalk gangliogliomas: Case report and literature review

OA Omofoye, M Lechpammer, TO Steele… - Clinical Neurology and …, 2021 - Elsevier
Introduction Gangliogliomas rarely occur in the sella or suprasellar region and are almost
never seen in the pituitary stalk. Seven cases of gangliogliomas occurring in this region …

Heterogeneity and excitability of BRAFV600E-induced tumors is determined by PI3K/mTOR-signaling state and Trp53-loss

S Cases-Cunillera, KMJ van Loo, J Pitsch… - bioRxiv, 2021 - biorxiv.org
Background Developmental brain tumors harboring BRAF V600E somatic mutation are
diverse. Here, we describe molecular factors that determine BRAF V600E-induced tumor …

[PDF][PDF] Mechanisms of epileptogenesis in animal models of developmental brain lesions

BK Robens - 2016 - d-nb.info
Epilepsy is a syndrome characterized by unpredictable, recurrent seizures a ecting
approximately 50 million people of all ages and is therefore regarded as one of the most …

Cerebellar Ganglioglioma in Childhood: Histopathologic Implications for Management During Long-term Survival: A Case Report

K Ohno, Y Saito, A Tamasaki-Kondo, A Kambe… - Yonago Acta …, 2017 - jstage.jst.go.jp
We report the case of a 19-year-old female with cerebellar ganglioglioma that was
diagnosed at 4 years of age. Despite treatment with partial resection, radiation, and …