The role of survival motor neuron protein (SMN) in protein homeostasis

H Chaytow, YT Huang, TH Gillingwater… - Cellular and Molecular …, 2018 - Springer
Ever since loss of survival motor neuron (SMN) protein was identified as the direct cause of
the childhood inherited neurodegenerative disorder spinal muscular atrophy, significant …

Targeting metabolic disorders by natural products

O Tabatabaei-Malazy, B Larijani… - Journal of Diabetes & …, 2015 - Springer
The most prevalent metabolic disorders are diabetes mellitus, obesity, dyslipidemia,
osteoporosis and metabolic syndrome, which are developed when normal metabolic …

[HTML][HTML] PoLA/CFPiP/PCS/PSLD/PSD/PSH guidelines on diagnosis and therapy of lipid disorders in Poland 2021

M Banach, P Burchardt, K Chlebus… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …

[HTML][HTML] Efficacy and safety of lipid lowering by alirocumab in chronic kidney disease

PP Toth, JP Dwyer, CP Cannon, HM Colhoun… - Kidney international, 2018 - Elsevier
Individuals with chronic kidney disease are at increased risk of premature cardiovascular
disease. Among them, many with elevated low-density lipoprotein cholesterol (LDL-C) are …

Lipotoxicity as a trigger factor of renal disease

A Izquierdo-Lahuerta, C Martínez-García… - Journal of …, 2016 - Springer
In the last few decades, rapid changes in lifestyle have led to an alarming increase in the
prevalence of obesity and obesity-associated complications. Obese patients are at …

Statins decrease all-cause mortality only in CKD patients not requiring dialysis therapy—a meta-analysis of 11 randomized controlled trials involving 21,295 …

M Barylski, S Nikfar, DP Mikhailidis, PP Toth… - Pharmacological …, 2013 - Elsevier
The available studies have reported the benefits of statins on all-cause and cardiovascular
mortality in chronic kidney disease (CKD) patients. However studies in end-stage renal …

A meta-analysis of the role of statins on renal outcomes in patients with chronic kidney disease. Is the duration of therapy important?

D Nikolic, M Banach, S Nikfar, P Salari… - International journal of …, 2013 - Elsevier
Introduction The efficacy of statin treatment in chronic kidney disease (CKD) patients
remains controversial. Therefore, we performed a meta-analysis to investigate whether …

Lipid, blood pressure and kidney update 2013

M Banach, C Serban, WS Aronow, J Rysz… - … urology and nephrology, 2014 - Springer
The year 2013 proved to be very exciting as far as landmark trials and new guidelines in the
field of lipid disorders, blood pressure and kidney diseases. Among these are the …

Framing cause-effect relationship of acute coronary syndrome in patients with chronic kidney disease

MI Moisi, SG Bungau, CM Vesa, CC Diaconu, T Behl… - Diagnostics, 2021 - mdpi.com
The main causes of death in patients with chronic kidney disease (CKD) are of
cardiovascular nature. The interaction between traditional cardiovascular risk factors (CVRF) …

Metabolic syndrome and non-cardiac vascular diseases: an update from human studies

N Katsiki, VG Athyros, A Karagiannis… - Current …, 2014 - ingentaconnect.com
The metabolic syndrome (MetS) is characterized by a cluster of risk factors including central
obesity, hypertension, dyslipidemia and insulin resistance, The MetS is associated with an …