Simple Summary Giant cell tumor of bone (GCTB) is an aggressive non-cancerous bone
tumor. Surgery remains the main treatment for GCTB. Denosumab has been approved for …

Context.—Immunohistochemistry plays an important role in dermatopathology, particularly
for melanocytic lesions and poorly differentiated malignancies. In the field of bone and soft …

Historically, the diagnosis of giant cell-rich neoplasms arising in bone has been challenging
owing to overlapping clinical and radiographic findings resulting in the difficult separation of …

Giant cell tumor of bone (GCTB) undergoes a sarcomatous transformation. Secondary
malignancy in giant cell tumor (MGCT) is associated with radiotherapy and has a dismal …

目的探讨地舒单抗(Denosumab) 治疗后伴有假肉瘤样改变和高核分裂活性的骨巨细胞瘤的组织
形态特征, 诊断及鉴别诊断. 方法回顾性分析广州医科大学附属第二医院收治的1 …

Giant cell tumors of the bone (GCTB) are considered moderately malignant bone tumors.
Denosumab, as a neoadjuvant therapy, provides new possibilities for treating GCTB …