Additive genetic variance (VA) reflects the potential for evolutionary shifts and can be low for
some traits or populations. High VA is critical for the conservation of threatened species …

The goal of this review article is to provide a conceptual based summary of how heritability
estimates for complex traits such as obesity are determined and to explore the future …

Data on hundreds or thousands of single nucleotide polymorphisms (SNPs) provide detailed
information about the relationships between individuals, but currently few tools can turn this …

Inbreeding depression is of major concern for the conservation of threatened species, and
inbreeding avoidance is thought to be a key driver in the evolution of mating systems …

In this study, we used insurance claims for over one-third of the entire US population to
create a subset of 128,989 families (481,657 unique individuals). We then used these data …

Methods for inference and interpretation of evolutionary quantitative genetic parameters,
and for prediction of the response to selection, are best developed for traits with normal …

Genetic erosion is a major threat to biodiversity because it can reduce fitness and ultimately
contribute to the extinction of populations. Here, we explore the use of quantitative metrics to …

Inbreeding depression is ubiquitous, but we still know little about its genetic architecture and
precise effects in wild populations. Here, we combine long-term life-history data with 417 K …

The concept of kinship permeates many domains of fundamental and applied biology
ranging from social evolution to conservation science to quantitative and human genetics …

Unraveling the genetic basis of organismal form and function remains one of the major goals
of evolutionary biology. Theory has long supported a model of polygenic evolution in which …