The complex polymicrobial composition of human gut microbiota plays a key role in health
and disease. Lachnospiraceae belong to the core of gut microbiota, colonizing the intestinal …

Actions of symbiotic gut microbiota are in dynamic balance with the host's organism to
maintain homeostasis. Many different factors have an impact on this relationship, including …

While modulatory effects of gut microbes on neurological phenotypes have been reported,
the mechanisms remain largely unknown. Here, we demonstrate that indole, a tryptophan …

Cardiovascular disease (CVD) is the leading cause of death in Western countries,
representing almost 30% of all deaths worldwide. Evidence shows the effectiveness of …

Trillions of microbes have evolved with and continue to live on human beings. With the rapid
advances in tools and technology in recent years, new knowledge and insight in cross-talk …

The essential amino acid tryptophan (Trp) is metabolized by gut commensals, yielding in
compounds that affect innate immune cell functions directly, but also acting on the aryl …

The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …

Background High‐resistance inspiratory muscle strength training (IMST) is a novel, time‐
efficient physical training modality. Methods and Results We performed a double‐blind …

Butyric acid (BA) is a short-chain fatty acid (SCFA) produced by gut bacteria in the colon. We
hypothesized that colon-derived BA may affect hemodynamics. Arterial blood pressure (BP) …

Indole and its derivatives are widespread across different life forms, functioning as signalling
molecules in prokaryotes and with more diverse roles in eukaryotes. A majority of indoles …