Background Inappropriate medication prescription is a common cause of preventable
adverse drug events among elderly persons in the primary care setting. Objective The aim of …

BACKGROUND: Elderly patients are vulnerable to drug interactions because of age-related
physiologic changes, an increased risk for disease associated with aging, and the …

Background: The Beers criteria identify inappropriate use of medications in older adults. The
number of and risk for adverse events from these medications are unknown. Objective: To …

Background At some point in life, virtually everyone experiences some type of pain. Pain is
often classified as acute or chronic. Acute pain, such as postoperative pain, subsides as …

Background: The extent of medical and financial problems of polypharmacy in the elderly is
disturbing, particularly in nursing homes and nursing departments. Objectives: To improve …

Introduction The proportion of the elderly is constantly increasing and by the year 2025 20%
of the population will be above 65 years of age. With advanced age, subjects will develop …

Context Understanding and improving the quality of medication management is particularly
important in the context of the Medicare prescription drug benefit that took effect last January …

The cytochrome P450 enzymes (P450s or CYPs) are a class of heme-containing
monooxygenases responsible for the oxidative metabolism of a wide range of endogenous …

Drug–drug interactions (DDI) occurring with potentially inappropriate medications (PIM) are
additional risk factors that may increase the inappropriate character of PIM. The aim of this …

BACKGROUND:: Studies indicate that adverse drug events (ADEs) are common and costly.
It appears that the elderly are at greater risk of ADEs because they use more medications …