Parkinson's disease (PD) is the most common neurological movement disorder
characterized by the selective and irreversible loss of dopaminergic neurons in substantia …

The conversion of otherwise soluble proteins into insoluble amyloid aggregates is
associated with a range of neurodegenerative disorders, including Alzheimer's and …

Disruption of cell membranes by Aβ is believed to be one of the key components of Aβ
toxicity. However, the mechanism by which this occurs is not fully understood. Here, we …

The interplay between α-synuclein (α-syn) and catechols plays a central role in Parkinson's
disease. This may be related to the modulating effects of catechols on the various aspects of …

Alzheimer's disease (AD), the most prevalent form of dementia, remains incurable mainly
due to our failings in the search for effective pharmacological strategies. Here, we describe …

Disruption of the integrity of the plasma membrane by amyloidogenic proteins is linked to the
pathogenesis of a number of common age-related diseases. Although accumulating …

Heating aqueous solutions of ovalbumin (OVA) may cause gel formation. When heated at
pH conditions close to the protein's isoelectric point (towards neutral pH), turbid particulate …

Proteins, showing non-conjugated and nonaromatic structures, have been discovered with
abnormal visible emission at the clustering state, namely clusteroluminescence (CL) …

In several neurodegenerative diseases, cell toxicity can emerge from damage produced by
amyloid aggregates to lipid membranes. The details accounting for this damage are poorly …

An increasing number of studies conducted under in vitro and in vivo conditions, have
concluded that polyphenols, compounds frequently occurring in many herbs with antioxidant …