A comprehensive review of chalcone derivatives as antileishmanial agents
MVP de Mello, B de Azevedo Abrahim-Vieira… - European journal of …, 2018 - Elsevier
Leishmaniasis is a group of infectious neglected tropical diseases caused by more than 20
pathogenic species of Leishmania sp. Due to the limitations of the current treatments …
pathogenic species of Leishmania sp. Due to the limitations of the current treatments …
Antileishmanial drug discovery: Comprehensive review of the last 10 years
Leishmaniasis, a group of diseases caused by hemoflagellate obligate intracellular protozoa
(trypanosomatids) from the genus Leishmania, has not received the attention it deserves …
(trypanosomatids) from the genus Leishmania, has not received the attention it deserves …
A review on new natural and synthetic anti-leishmanial chemotherapeutic agents and current perspective of treatment approaches.
N Majumder, A Banerjee, S Saha - Acta Tropica, 2023 - Elsevier
Leishmaniases are considered among the most neglected yet dangerous parasitic diseases
worldwide. According to the recent WHO report (Weekly Epidemiological Record, Sep …
worldwide. According to the recent WHO report (Weekly Epidemiological Record, Sep …
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase
All currently used first-line and second-line drugs for the treatment of leishmaniasis exhibit
several drawbacks including toxicity, high costs and route of administration. Furthermore …
several drawbacks including toxicity, high costs and route of administration. Furthermore …
Design, synthesis, cytotoxicity, HuTopoIIα inhibitory activity and molecular docking studies of pyrazole derivatives as potential anticancer agents
In an attempt to find potential anticancer agents, a series of novel ethyl 4-(3-(aryl)-1-phenyl-
1H-pyrazol-4-yl)-2-oxo-6-(pyridin-3-yl) cyclohex-3-enecarboxylates 5a-i and 5-(3-(4 …
1H-pyrazol-4-yl)-2-oxo-6-(pyridin-3-yl) cyclohex-3-enecarboxylates 5a-i and 5-(3-(4 …
Synthesis, structural characterization and computational study of a novel amino chalcone: a potential nonlinear optical material
LR Almeida, MM Anjos, GC Ribeiro… - New Journal of …, 2017 - pubs.rsc.org
The interest for novel chalcone-based materials in nonlinear optics is dependent on strong
second harmonic generation in organic systems. Chalcones are α, β-unsaturated ketones …
second harmonic generation in organic systems. Chalcones are α, β-unsaturated ketones …
The chemotherapeutic potential of chalcones against leishmaniases: a review
Leishmaniases are endemic diseases in tropical and sub-tropical regions of the world and
are considered by the World Health Organization (WHO) to be among the six most important …
are considered by the World Health Organization (WHO) to be among the six most important …
[HTML][HTML] Identification of some chalcone analogues as potential antileishmanial agents: An integrated in vitro and in silico evaluation
MS Osman, TA Awad, SW Shantier… - Arabian Journal of …, 2022 - Elsevier
Chalcones, either natural or synthetic, are known to exhibit various biological activities. The
present study aimed to evaluate the in vitro and in silico activities of some chalcone …
present study aimed to evaluate the in vitro and in silico activities of some chalcone …
Current therapeutics, their problems and thiol metabolism as potential drug targets in leishmaniasis
Leishmaniasis is one of the six diseases regarded most neglected by World Health
Organization which is predominant in developing countries. Clinically, among the different …
Organization which is predominant in developing countries. Clinically, among the different …
Novel amino-pyrazole ureas with potent in vitro and in vivo antileishmanial activity
CE Mowbray, S Braillard, W Speed… - Journal of medicinal …, 2015 - ACS Publications
Visceral leishmaniasis is a severe parasitic disease that is one of the most neglected tropical
diseases. Treatment options are limited, and there is an urgent need for new therapeutic …
diseases. Treatment options are limited, and there is an urgent need for new therapeutic …