Nanoparticles for targeted brain drug delivery: what do we know?

RGR Pinheiro, AJ Coutinho, M Pinheiro… - International Journal of …, 2021 - mdpi.com
The blood–brain barrier (BBB) is a barrier that separates the blood from the brain tissue and
possesses unique characteristics that make the delivery of drugs to the brain a great …

Crossing the blood-brain barrier with nanoparticles

Y Zhou, Z Peng, ES Seven, RM Leblanc - Journal of controlled release, 2018 - Elsevier
The blood-brain barrier (BBB) is one of the most essential protection mechanisms in the
central nervous system (CNS). It selectively allows individual molecules such as small lipid …

A deep investigation into the structure of carbon dots

KJ Mintz, M Bartoli, M Rovere, Y Zhou… - Carbon, 2021 - Elsevier
Since their discovery, carbon dots (CDs) have been a promising nanomaterial in a variety of
fields including nanomedicine. Despite their potential in this area, there are many obstacles …

Targeting the transferrin receptor for brain drug delivery

KB Johnsen, A Burkhart, LB Thomsen… - Progress in …, 2019 - Elsevier
Obtaining efficient drug delivery to the brain remains the biggest challenge for the
development of therapeutics to treat diseases of the central nervous system. The main …

An overview on carbon quantum dots optical and chemical features

MG Giordano, G Seganti, M Bartoli, A Tagliaferro - Molecules, 2023 - mdpi.com
Carbon quantum dots are the materials of a new era with astonishing properties such as
high photoluminescence, chemical tuneability and high biocompatibility. Since their …

Carbon dots: biomacromolecule interaction, bioimaging and nanomedicine

Z Peng, X Han, S Li, AO Al-Youbi… - Coordination chemistry …, 2017 - Elsevier
Carbon dots, a recent member of the renowned carbon-based nanomaterials family, have
attracted significant interest from various fields. The extraordinary properties, including …

Carbon dots: A future Blood–Brain Barrier penetrating nanomedicine and drug nanocarrier

W Zhang, G Sigdel, KJ Mintz, ES Seven… - International journal …, 2021 - Taylor & Francis
Drug delivery across the blood–brain barrier (BBB) is one of the biggest challenges in
modern medicine due to the BBB's highly semipermeable property that limits most …

Carbon dots: an innovative tool for drug delivery in brain tumors

G Calabrese, G De Luca, G Nocito, MG Rizzo… - International Journal of …, 2021 - mdpi.com
Simple Summary The pharmacological treatment of tumors of the central nervous system
poses major challenges due to the presence of physical obstacles, ie, the blood-brain …

Cancer targeting and drug delivery using carbon-based quantum dots and nanotubes

J Pardo, Z Peng, RM Leblanc - Molecules, 2018 - mdpi.com
Currently cancer treatment is in large part non-specific with respect to treatment. Medication
is often harsh on patients, whereby they suffer several undesired side effects as a result …

Carbon dots as versatile nanoarchitectures for the treatment of neurological disorders and their theranostic applications: A review

M Ashrafizadeh, R Mohammadinejad… - Advances in colloid and …, 2020 - Elsevier
The development of novel methods plays a fundamental role in early diagnosis and
controlling of neurological disorders (NDs). Blood-brain barrier (BBB) is the most …